Add to ORKGHexahydroindenes 10 are readily available in 3 steps with an overall yield of 41 – 45 % starting from the Hajos Wiechert ketone 1. Alkylation of the α,β-unsaturated ketone 1 at C-4 has been achieved by thioalkylation of the corresponding zinc dienolate 2 with α-chlorosulfides of type 3. Subsequent in situ reduction and desulfurization of the β-(phenylthio) ketones 4 leads directly to the 4-substituted hexahydroindene-5-ols 6 which can be deoxygenated via their mesylates to the hexahydroindenes 10.publishe
Steroid Research Laboratory, Department of Chemistry, Aligarh Muslim University, Aligarh-202 001 Man...
The hitherto unknown 5,6-dihydroxy-3-mercaptoindole (4a) and its 2-carbomethoxy derivative (4b), as ...
In the first part of this thesis an intramolecular alkylation study involving 4a-(3-chloropropy1)-4,...
Hexahydroindenes 10 are readily available in 3 steps with an overall yield of 41 – 45 % starting fro...
α-Alkylation of the α,β-unsaturated ketone 1 at C-4 has been achieved by thioalkylation of the corre...
An α-alkylation of the 2-methylcycloalkanones 1 and 4 at the higher substituted carbon can be achiev...
This thesis is divided into three parts. Part 1 describes the chemistry of dilithium (trimethylstann...
A general method for the synthesis of thiophens and endothiothiophens has been described. The antoco...
Silyl enol ethers (2) react with tributyl [(phenylthio) chloromethyl] stannane (1) in the presence o...
A short and stereoselective synthesis of hexadeuterated hexestrol is described, involving catalytic ...
Thioalkylated Meldrum’s acid is easily available by treatment of Meldrum’s acid with an aldehyde and...
The conversion of β-keto esters into β-methylated γ-keto esters can be achieved through treatment wi...
alfa-Ketosulphides of benzothiazole 1 react with allylic carbonates in the presence of palladium ac...
Thioalkylated Meldrum 's acid is easily by treatment of Meldrum 's acid with an aldehyde and thiop...
A new and appropriate synthesis for hexahydro-1H-isoindole-1,3(2H)-dione derivatives has been develo...
Steroid Research Laboratory, Department of Chemistry, Aligarh Muslim University, Aligarh-202 001 Man...
The hitherto unknown 5,6-dihydroxy-3-mercaptoindole (4a) and its 2-carbomethoxy derivative (4b), as ...
In the first part of this thesis an intramolecular alkylation study involving 4a-(3-chloropropy1)-4,...
Hexahydroindenes 10 are readily available in 3 steps with an overall yield of 41 – 45 % starting fro...
α-Alkylation of the α,β-unsaturated ketone 1 at C-4 has been achieved by thioalkylation of the corre...
An α-alkylation of the 2-methylcycloalkanones 1 and 4 at the higher substituted carbon can be achiev...
This thesis is divided into three parts. Part 1 describes the chemistry of dilithium (trimethylstann...
A general method for the synthesis of thiophens and endothiothiophens has been described. The antoco...
Silyl enol ethers (2) react with tributyl [(phenylthio) chloromethyl] stannane (1) in the presence o...
A short and stereoselective synthesis of hexadeuterated hexestrol is described, involving catalytic ...
Thioalkylated Meldrum’s acid is easily available by treatment of Meldrum’s acid with an aldehyde and...
The conversion of β-keto esters into β-methylated γ-keto esters can be achieved through treatment wi...
alfa-Ketosulphides of benzothiazole 1 react with allylic carbonates in the presence of palladium ac...
Thioalkylated Meldrum 's acid is easily by treatment of Meldrum 's acid with an aldehyde and thiop...
A new and appropriate synthesis for hexahydro-1H-isoindole-1,3(2H)-dione derivatives has been develo...
Steroid Research Laboratory, Department of Chemistry, Aligarh Muslim University, Aligarh-202 001 Man...
The hitherto unknown 5,6-dihydroxy-3-mercaptoindole (4a) and its 2-carbomethoxy derivative (4b), as ...
In the first part of this thesis an intramolecular alkylation study involving 4a-(3-chloropropy1)-4,...