Add to ORKGThe ubiquitin-dependent N-end rule pathway targets proteins for degradation through their destabilizing N-terminal residues. This pathway is known to control the import of peptides, chromosome stability and cardiovascular development. A new report identifies yet another function of the N-end rule pathway: the regulation of apoptosis through degradation of Drosophila melanogaster DIAP1
Eukaryotes contain a highly conserved multienzyme system which covalently links a small protein, ubi...
The N-end rule pathway is a protein degradation pathway that relates the stability of a protein to t...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2002.Includes bibliographi...
The ubiquitin-dependent N-end rule pathway targets proteins for degradation through their destabiliz...
A pivotal hallmark of some cancer cells is the evasion of apoptotic cell death. Importantly, the ini...
Inhibitor of apoptosis proteins (IAPs) act as endogenous inhibitors of active caspases. Drosophila I...
The activity and abundance of proteins within a cell are controlled precisely to ensure the regulat...
The N-end rule links the identity of the N-terminal amino acid of a protein to its in vivo half life...
The N-end rule relates the in vivo half-life of a protein to the identity of its N-terminal residue....
Apoptosis is an evolutionarily conserved, actively regulated cell death process that plays an essent...
The N-end rule pathway relates the in vivo half-life of a protein to the identity of its N terminal ...
The N-end rule pathway is a highly conserved process that operates in many different organisms. It r...
The N-end rule relates the in vivo half-life of a protein to the identity of its amino-terminal resi...
Eukaryotes contain a highly conserved multienzyme system which covalently links a small protein, ubi...
<p>The <i>Drosophila</i> caspase Dronc, which is required for fly development, is composed of an N-t...
Eukaryotes contain a highly conserved multienzyme system which covalently links a small protein, ubi...
The N-end rule pathway is a protein degradation pathway that relates the stability of a protein to t...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2002.Includes bibliographi...
The ubiquitin-dependent N-end rule pathway targets proteins for degradation through their destabiliz...
A pivotal hallmark of some cancer cells is the evasion of apoptotic cell death. Importantly, the ini...
Inhibitor of apoptosis proteins (IAPs) act as endogenous inhibitors of active caspases. Drosophila I...
The activity and abundance of proteins within a cell are controlled precisely to ensure the regulat...
The N-end rule links the identity of the N-terminal amino acid of a protein to its in vivo half life...
The N-end rule relates the in vivo half-life of a protein to the identity of its N-terminal residue....
Apoptosis is an evolutionarily conserved, actively regulated cell death process that plays an essent...
The N-end rule pathway relates the in vivo half-life of a protein to the identity of its N terminal ...
The N-end rule pathway is a highly conserved process that operates in many different organisms. It r...
The N-end rule relates the in vivo half-life of a protein to the identity of its amino-terminal resi...
Eukaryotes contain a highly conserved multienzyme system which covalently links a small protein, ubi...
<p>The <i>Drosophila</i> caspase Dronc, which is required for fly development, is composed of an N-t...
Eukaryotes contain a highly conserved multienzyme system which covalently links a small protein, ubi...
The N-end rule pathway is a protein degradation pathway that relates the stability of a protein to t...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2002.Includes bibliographi...