Stem cell transplantation for type 1 diabetes mellitus

Abstract\ud \ud \ud \ud Background\ud \ud The use of stem cells to treat type 1 diabetes mellitus has been proposed for many years, both to downregulate the immune system and to provide β cell regeneration.\ud \ud \ud \ud Conclusion\ud \ud High dose immunosuppression followed by autologous hematopoietic stem cell transplantation is able to induce complete remission (insulin independence) in most patients with early onset type 1 diabetes mellitus