Add to ORKGRifampicin at various dose levels was injected intraperitoneally (ip) into Swiss Albino male mice for a period of one week. The S9 fraction prepared from tbe animals given 80 mg (per kg body weight) induced a significant number of revertants in tbe TA9S strain of Salmonella typhimurium. Rifampicin treatment of mice was also found to induce the activity of hepatic aryl hydrocarbon hydroxylase. Isoniazid (INH) added in vitro at therapeutic concentration (15/ig/plate) was not mutagenic either to TA98 or TA100 strain of S. typhimurium in the presence of rifampicin induced Sf fraction
AbstractObjectiveTo investigate the cellular toxicity of isoniazid together with rifampicin and the ...
This in vitro mutagenicity test system comprises five different strains of S. typhimurium as target ...
hydrocarbon mixtures were tested directly, without extraction, in the Salmonella/toicrosome mutagene...
Rifampicin (Rif) is an effective liver enzyme inducer, promoting the up-regulation of hepatic cytoch...
Rifampicin which is a known antituberculous agent has been reported to induce both chromosomal break...
Research on the influence of isoniazid on rifampicin metabolism using rat hepatocytes has been done....
To investigate the antagonism between isoniazid (INH) and rifampin (rifampicin) (RIF)-pyrazinamide (...
2To whom correspondence should be addressed 1,8-Dinitropyrene (DNP) is a potent, direct-acting mutag...
ABSTRACT-The mutagenic activity of 101 chemicals was stud-Ied wHh the use of the Salmonella Iyphlmur...
Chemicals/CAS: hydrazine, 10217-52-4, 13775-80-9, 18500-32-8, 302-01-2, 7803-57-8; isoniazid, 54-85-...
In this study, the mutagenicity of the anti-inflammatory parsalmide [5-amino-N-butyl-2-(2-propynylox...
The mutagenicity of several test compounds was verified by the Salmonella/microsome mutagenicity tes...
The objective of this study was to examine the effect of rifampin pretreatment on isoniazid-induced...
Screening of a S. typhimurium promoter-luxCDABE fusion library revealed that the antibiotic rifampic...
Genetic toxicology assays have been used to investigate the mechanisms and modes of actions, both in...
AbstractObjectiveTo investigate the cellular toxicity of isoniazid together with rifampicin and the ...
This in vitro mutagenicity test system comprises five different strains of S. typhimurium as target ...
hydrocarbon mixtures were tested directly, without extraction, in the Salmonella/toicrosome mutagene...
Rifampicin (Rif) is an effective liver enzyme inducer, promoting the up-regulation of hepatic cytoch...
Rifampicin which is a known antituberculous agent has been reported to induce both chromosomal break...
Research on the influence of isoniazid on rifampicin metabolism using rat hepatocytes has been done....
To investigate the antagonism between isoniazid (INH) and rifampin (rifampicin) (RIF)-pyrazinamide (...
2To whom correspondence should be addressed 1,8-Dinitropyrene (DNP) is a potent, direct-acting mutag...
ABSTRACT-The mutagenic activity of 101 chemicals was stud-Ied wHh the use of the Salmonella Iyphlmur...
Chemicals/CAS: hydrazine, 10217-52-4, 13775-80-9, 18500-32-8, 302-01-2, 7803-57-8; isoniazid, 54-85-...
In this study, the mutagenicity of the anti-inflammatory parsalmide [5-amino-N-butyl-2-(2-propynylox...
The mutagenicity of several test compounds was verified by the Salmonella/microsome mutagenicity tes...
The objective of this study was to examine the effect of rifampin pretreatment on isoniazid-induced...
Screening of a S. typhimurium promoter-luxCDABE fusion library revealed that the antibiotic rifampic...
Genetic toxicology assays have been used to investigate the mechanisms and modes of actions, both in...
AbstractObjectiveTo investigate the cellular toxicity of isoniazid together with rifampicin and the ...
This in vitro mutagenicity test system comprises five different strains of S. typhimurium as target ...
hydrocarbon mixtures were tested directly, without extraction, in the Salmonella/toicrosome mutagene...