Proteins of the brain and body wall in larvae of Drosophila melanogaster

Proteins of the brain and body wall cells of third instar larvae ofDrosophila melano-gaster have been examined by two-dimensional gel electrophoresis. Out of over 600 [35S]-labelled peptide spots seen in brain or body wall extracts, 517 were common to both; 61 spots were unique to brain and 66 unique to muscle. Glycoproteins were identified by soaking the gels in radioactive iodinated Concanavalin-A. Forty four Con-A binding glycoproteins were identifiable in the brain and 41 in the muscle extracts. Out of these, 8 glycoproteins of the brain and 8 of muscles appear to be tissue-specific