Studies directed towards the synthesis of rapamycin: stereoselective synthesis of C-1 to C-15 segment
- Rama Rao, A. V.
- Desibhatla, Vidyanand
DOIAbstract
Stereoselective synthesis of a suitably functionalized C-1 to C-15 segment of rapamycin is described
Stereoselective synthesis of a suitably functionalized C-1 to C-15 segment of rapamycin is described
An efficient and convergent synthesis of the C<sub>5</sub>–C<sub>18</sub> fragment of halichomycin i...
Reaction of trimethylaluminium, dimethyllithium cuprate and lithium tetramethylaluminate with the ho...
An efficient and convergent synthesis of the C-5-C-18 fragment of halichomycin is reported. Butanoli...
Stereoselective synthesis of a suitably functionalized C-1 to C-15 segment of rapamycin is described
This dissertation describes a stereoselective synthesis of two major fragments of rapamycin. Isolate...
A stereoselective construction of the C21-C42 fragment 2 of rapamycin 1via coupling and elaboration ...
A strategy for a total synthesis of the immunosuppressant agent rapamycin 1 is outlined and the ster...
This dissertation describes synthetic studies culminating in the total synthesis of the macrocyclic ...
A stereoselective synthesis of a rapamycin fragment is developed and further utilized toward buildin...
Stereoselective synthesis of a peptidomimetic analog of the binding domain of rapamycin starting fro...
Details of the total synthesis of rapamycin (1) are reported. The synthesis required the preparation...
The main contributions of the work described in this thesis are the development of a novel method fo...
A stereoselective synthesis of a rapamycin fragment is developed and further utilized toward buildin...
The macrolide rapamycin ( 1 ) was first described as an antifungal agent in 1975. Even though its bi...
For over 30 years, rapamycin has generated a sustained and intense interest from the scientific comm...
An efficient and convergent synthesis of the C<sub>5</sub>–C<sub>18</sub> fragment of halichomycin i...
Reaction of trimethylaluminium, dimethyllithium cuprate and lithium tetramethylaluminate with the ho...
An efficient and convergent synthesis of the C-5-C-18 fragment of halichomycin is reported. Butanoli...
Stereoselective synthesis of a suitably functionalized C-1 to C-15 segment of rapamycin is described
This dissertation describes a stereoselective synthesis of two major fragments of rapamycin. Isolate...
A stereoselective construction of the C21-C42 fragment 2 of rapamycin 1via coupling and elaboration ...
A strategy for a total synthesis of the immunosuppressant agent rapamycin 1 is outlined and the ster...
This dissertation describes synthetic studies culminating in the total synthesis of the macrocyclic ...
A stereoselective synthesis of a rapamycin fragment is developed and further utilized toward buildin...
Stereoselective synthesis of a peptidomimetic analog of the binding domain of rapamycin starting fro...
Details of the total synthesis of rapamycin (1) are reported. The synthesis required the preparation...
The main contributions of the work described in this thesis are the development of a novel method fo...
A stereoselective synthesis of a rapamycin fragment is developed and further utilized toward buildin...
The macrolide rapamycin ( 1 ) was first described as an antifungal agent in 1975. Even though its bi...
For over 30 years, rapamycin has generated a sustained and intense interest from the scientific comm...
An efficient and convergent synthesis of the C<sub>5</sub>–C<sub>18</sub> fragment of halichomycin i...
Reaction of trimethylaluminium, dimethyllithium cuprate and lithium tetramethylaluminate with the ho...
An efficient and convergent synthesis of the C-5-C-18 fragment of halichomycin is reported. Butanoli...
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