Background. Sensitized patients (pts) may develop acute antibody-mediated rejection (AMR) due to preformed donor-specific antibodies, undetected by pre-transplant complement-dependent cytotoxicity (CDC) crossmatch (XM). We hypothesized that C4d staining in 1-h post-reperfusion biopsies (1-h Bx) could detect early complement activation in the renal allograft due to preformed donor-specific antibodies. Methods. To test this hypothesis, renal transplants (n = 229) performed between June 2005 and December 2007 were entered into a prospective study of 1-h Bx and stained for C4d by immunofluorescence. Transplants were performed against a negative T-cell CDC-XM with the exception of three cases with a positive B-cell XM. Results. All 229 1-h Bx st...
T cell-mediated acute rejection (ATCMR) in renal transplant patients can have an antibody-mediated c...
Annual Meeting of the Turkish-Transplantation-Society -- JUL 04-06, 2007 -- Ankara, TURKEYWOS: 00025...
Acute humoral rejection (AHR) is difficult to diagnose and portends a poor renal transplant outcome...
Background. Sensitized patients (pts) may develop acute antibody-mediated rejection (AMR) due to pre...
Background: C4d as a part of complement activation process is a marker for detecting antibody-mediat...
Capillary C4d deposition has been recognized as a marker of antibody-mediated rejection (AMR). Altho...
Introduction: C4d staining in peritubular capillaries strongly correlates with presence of acute or ...
Introduction: C4d staining in peritubular capillaries strongly correlates with presence of acute or ...
In this study, we conducted a systematic review of the literature to re-evaluate the role of C4d in ...
BACKGROUND: Detection of C4d along peritubular capillaries (PTC) in renal allograft biopsies is an i...
The immunohistochemical detection of the complement degradation product C4d in renal allograft biops...
PubMed ID: 18261578Recent studies showed that peritubular capillary deposition of C4d is a marker of...
Introduction. Peritubular capillary complement 4d staining is one of the criteria for the diagnosis ...
A false-positive complement-dependent cytotoxicity cross-match (CDC XM) has a negative impact in don...
Peritubular capillary (PTC) C4d staining represents a marker for acute humoral rejection, however, t...
T cell-mediated acute rejection (ATCMR) in renal transplant patients can have an antibody-mediated c...
Annual Meeting of the Turkish-Transplantation-Society -- JUL 04-06, 2007 -- Ankara, TURKEYWOS: 00025...
Acute humoral rejection (AHR) is difficult to diagnose and portends a poor renal transplant outcome...
Background. Sensitized patients (pts) may develop acute antibody-mediated rejection (AMR) due to pre...
Background: C4d as a part of complement activation process is a marker for detecting antibody-mediat...
Capillary C4d deposition has been recognized as a marker of antibody-mediated rejection (AMR). Altho...
Introduction: C4d staining in peritubular capillaries strongly correlates with presence of acute or ...
Introduction: C4d staining in peritubular capillaries strongly correlates with presence of acute or ...
In this study, we conducted a systematic review of the literature to re-evaluate the role of C4d in ...
BACKGROUND: Detection of C4d along peritubular capillaries (PTC) in renal allograft biopsies is an i...
The immunohistochemical detection of the complement degradation product C4d in renal allograft biops...
PubMed ID: 18261578Recent studies showed that peritubular capillary deposition of C4d is a marker of...
Introduction. Peritubular capillary complement 4d staining is one of the criteria for the diagnosis ...
A false-positive complement-dependent cytotoxicity cross-match (CDC XM) has a negative impact in don...
Peritubular capillary (PTC) C4d staining represents a marker for acute humoral rejection, however, t...
T cell-mediated acute rejection (ATCMR) in renal transplant patients can have an antibody-mediated c...
Annual Meeting of the Turkish-Transplantation-Society -- JUL 04-06, 2007 -- Ankara, TURKEYWOS: 00025...
Acute humoral rejection (AHR) is difficult to diagnose and portends a poor renal transplant outcome...