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S/2016/888 12/15 16-18485 between the actors identified by the Panel and the individual perpetrators and their chain of command, as well as sponsors and organizers. 50. As reflected in its third report, the Mechanism requested information concerning the production, possession and movement of chlorine by the Government of the Syrian Arab Republic. It also looked into the possession and movement of chlorine by terrorist groups, in particular the Nusrah Front, and armed opposition groups, given that a major chlorine production facility had been taken over by the Nusrah Front in August 2012. 51. The Leadership Panel notes with grave concern that, during the reporting period, the Mechanism received 13 allegations of possession, movement and/or intent of use of toxic substances, including chemical weapons, by non-State actors in the Syrian Arab Republic. They were referred to the OPCW technical secretariat. 52. The Leadership Panel reiterates once again its strong conviction that the use of chemicals as weapons, for any reason and under any circumstances, is totally abhorrent. The Panel also reaffirms its belief that it is crucial to hold those who use or intend to use chemicals as weapons accountable for their acts, given that it is fundamental to deter all those who continue to believe that there is something to be gained from the use of toxic chemicals as weapons. No reason can justify their use or intent of use as weapons by anybody, anywhere. If individuals, groups, entities or Governments perceive these weapons to be useful tools, no matter the costs, proliferation will ensue. The Panel therefore believes that those with effective control in the military units referred to in paragraph 30 of the present report must be held accountable. Accountability must also be applied to others responsible for the use of chemicals as weapons in the Syrian Arab Republic. 53. The Leadership Panel conveys its appreciation for the cooperation received from Member States and other entities in support of its work to date, including the generous financial contributions received. 54. Lastly, the Leadership Panel expresses its appreciation for the support received from the United Nations Secretariat, in particular the Office for Disarmament Affairs, and from the OPCW technical secretariat in delivering its mandate