Business continuity management is a comprehensive framework to prevent the disruptive events from impacting the business operations, quickly recovering business and reducing the corresponding potential damages for energy system, such as nuclear power plants (NPPs). This dissertation provides discussions on the following aspects: developing appropriate risk assessment methods in order to integrate condition monitoring data and inspection data for a robust and real-time risk profile updating and prognostics. To account for the uncertainty of condition monitoring data, a hidden Markov gaussian mixture model is developed to model the condition monitoring data. A Bayesian network is applied to integrate the two data sources. For improving applic...