Add to ORKGThe facile synthesis of seven new dicationic tripeptide benzyl ester derivatives, with hydrophobic group variations in the C-terminal amino acid component, is described. Moderate to good activity was seen against Gram-positive bacteria in vitro. One cyclohexyl-substituted compound 2c was tested more widely and showed good potency (MIC values ranging from 2–4 μg/mL) against antibiotic-resistant strains of Staphylococcus aureus and Enterococci (VRE, VSE), and against Staphylococcus epidermidis
A class of cyclic acyldepsipeptide antibiotics collectively known as the enopeptins has recently att...
Clostridioides (formerly Clostridium) difficile is a Gram-positive anaerobic bacterial pathogen that...
Toward delineation of antimicrobial action, a prototypic amphipathic, cationic decapeptide Ac-G-X-R-...
The facile synthesis of seven new dicationic tripeptide benzyl ester derivatives, with hydrophobic g...
An efficient synthesis of 29 new binaphthyl-based neutral, and mono- and di-cationic, peptoids is de...
The synthesis of eleven novel antibacterial agents is reported. The structures are based on a C2-sym...
[Extract] While the cationic glycopeptide vancomycin has long been regarded as the gold standard for...
The synthesis and properties of 80 short minor groove binders related to distamycin and the thiazotr...
The development of new antibiotics is of increasing importance due to the growing resistance power o...
As part of a programme investigating antibacterial cyclic macrocycles containing a cationic amino ac...
Clostridioides (also known as Clostridium) difficile is a Gram-positive anaerobic, spore producing b...
Clostridioides (also known as Clostridium) difficile is a Gram-positive anaerobic, spore producing b...
Antimicrobial peptides (AMPs) and their synthetic mimics have received recent interest as new altern...
Two sets of novel multiheaded cationic amphiphiles bearing one, two, and three trimethylammonium hea...
Clostridium difficile (C. difficile) is a problematic Gram positive bacterial pathogen causing moder...
A class of cyclic acyldepsipeptide antibiotics collectively known as the enopeptins has recently att...
Clostridioides (formerly Clostridium) difficile is a Gram-positive anaerobic bacterial pathogen that...
Toward delineation of antimicrobial action, a prototypic amphipathic, cationic decapeptide Ac-G-X-R-...
The facile synthesis of seven new dicationic tripeptide benzyl ester derivatives, with hydrophobic g...
An efficient synthesis of 29 new binaphthyl-based neutral, and mono- and di-cationic, peptoids is de...
The synthesis of eleven novel antibacterial agents is reported. The structures are based on a C2-sym...
[Extract] While the cationic glycopeptide vancomycin has long been regarded as the gold standard for...
The synthesis and properties of 80 short minor groove binders related to distamycin and the thiazotr...
The development of new antibiotics is of increasing importance due to the growing resistance power o...
As part of a programme investigating antibacterial cyclic macrocycles containing a cationic amino ac...
Clostridioides (also known as Clostridium) difficile is a Gram-positive anaerobic, spore producing b...
Clostridioides (also known as Clostridium) difficile is a Gram-positive anaerobic, spore producing b...
Antimicrobial peptides (AMPs) and their synthetic mimics have received recent interest as new altern...
Two sets of novel multiheaded cationic amphiphiles bearing one, two, and three trimethylammonium hea...
Clostridium difficile (C. difficile) is a problematic Gram positive bacterial pathogen causing moder...
A class of cyclic acyldepsipeptide antibiotics collectively known as the enopeptins has recently att...
Clostridioides (formerly Clostridium) difficile is a Gram-positive anaerobic bacterial pathogen that...
Toward delineation of antimicrobial action, a prototypic amphipathic, cationic decapeptide Ac-G-X-R-...