International audienceThe objective of this chapter is threefold: showing how research activity is spatially organized in the contemporary world at different scales, what are the different means and datasets available to measure its spatial distribution, and what can explain the degree of polarization of this activity. The chapter adopts a critical view on the literature that stresses the spatial polarization of this activity as if it was a necessary feature of it. First, the chapter demonstrates that contrary to most expectations, this polarization has globally diminished since the second part of the twentieth century. Second, taking the example of the regional distribution of research in Europe, it insists on the various means and sources...