Nontypeable Haemophilus influenzae (NTHi) is a common cause of infection of the respiratory tract in children and adults. The search for an effective vaccine against this pathogen has focused on components of the outer membrane, and peptidoglycan-associated lipoprotein P6 is among the proposed candidates. This study investigated the immunogenicity of P6 in a rat respiratory model. P6 was purified from two strains of NTHi, one capsule- deficient strain and an H. influenzae type b strain, and assessed for clearance of both homologous and heterologous bacterial strains following mucosal immunization. A protective immune response was determined by enhancement of pulmonary clearance of live bacteria and an increased rate of recruitment of phagoc...
Nontypeable Haemophilus influenzae (NTHi) causes respiratory infections that lead to high morbidity ...
The rat middle ear and lung clearance model has been used to show that the nontypeable Haemophilus i...
The rat middle ear and lung clearance model has been used to show that the nontypeable Haemophilus i...
Nontypeable Haemophilus influenzae (NTHi) is a common cause of infection of the respiratory tract in...
Nontypeable Haemophilus influenzae (NTHi) is a common cause of infection of the respiratory tract in...
A major outer membrane protein band of approximately 25 to 27 kDa is commonly observed in strains of...
This study investigates antigen-specific B and T cell responses following mucosal immunization with ...
Three strains of nontypeable Haemophilus influenzae namely NTHi-I, NTHi-II and NTHi-III were isolate...
Nontypeable Haemophilus influenzae (NTHi) or nonencapsulated Haemophilus influenzae has been connect...
Clearance of non-typeable Haemophilus influenzae (NTHi) from the respiratory tract was investigated,...
Pseudomonas aeruginosa is a major cause of nosocomal and community acquired chronic infections in su...
Clearance of non-typeable Haemophilus influenzae (NTHi) from the respiratory tract was investigated,...
The potential of empty bacterial cell envelopes (ghosts) as a delivery system for mucosal immunizati...
Haemophilus influenzae is a Gram-negative human-restricted bacterium that can act as a commensal and...
Haemophilus influenzae is a Gram-negative human-restricted bacterium that can act as a commensal and...
Nontypeable Haemophilus influenzae (NTHi) causes respiratory infections that lead to high morbidity ...
The rat middle ear and lung clearance model has been used to show that the nontypeable Haemophilus i...
The rat middle ear and lung clearance model has been used to show that the nontypeable Haemophilus i...
Nontypeable Haemophilus influenzae (NTHi) is a common cause of infection of the respiratory tract in...
Nontypeable Haemophilus influenzae (NTHi) is a common cause of infection of the respiratory tract in...
A major outer membrane protein band of approximately 25 to 27 kDa is commonly observed in strains of...
This study investigates antigen-specific B and T cell responses following mucosal immunization with ...
Three strains of nontypeable Haemophilus influenzae namely NTHi-I, NTHi-II and NTHi-III were isolate...
Nontypeable Haemophilus influenzae (NTHi) or nonencapsulated Haemophilus influenzae has been connect...
Clearance of non-typeable Haemophilus influenzae (NTHi) from the respiratory tract was investigated,...
Pseudomonas aeruginosa is a major cause of nosocomal and community acquired chronic infections in su...
Clearance of non-typeable Haemophilus influenzae (NTHi) from the respiratory tract was investigated,...
The potential of empty bacterial cell envelopes (ghosts) as a delivery system for mucosal immunizati...
Haemophilus influenzae is a Gram-negative human-restricted bacterium that can act as a commensal and...
Haemophilus influenzae is a Gram-negative human-restricted bacterium that can act as a commensal and...
Nontypeable Haemophilus influenzae (NTHi) causes respiratory infections that lead to high morbidity ...
The rat middle ear and lung clearance model has been used to show that the nontypeable Haemophilus i...
The rat middle ear and lung clearance model has been used to show that the nontypeable Haemophilus i...