Add to ORKGThe invention provides novel compounds based on piperazinylpyrimidine derivatives to be used as protein kinase inhibitors. The compounds may be useful in treating or preventing different cellular proliferation disorders, such as cancer. The present invention also provides methods of preparing these compounds, and methods of using the same
Substituted anthranilic acid and piperazines were used as building blocks to prepare two libraries o...
Compounds of the substituted pyrazole class as treatments for cancer are reported. A method of treat...
The present invention relates to piperazinone compounds, pharmaceutical compositions containing thos...
The present invention relates to certain 4-(substituted aniline)-2-(substituted piperidin-1-yl)pyrim...
This invention relates to pyrrolopyrimidine comprising compounds that may be useful as inhibitors of...
The subject invention concerns compositions and methods for blocking cancer cell growth or prolifera...
Compounds of the general formula (I) and salts thereof are useful in the treatment of diseases assoc...
The subject invention concerns materials and methods for inhibiting the Akt/PKB pathway. In one embo...
The present invention relates to 4-pyrimidinylamino-benzenesulfonamide derivatives of general formul...
The invention provides compounds of formula (I) wherein R is −CH3 or −CH2CH3 and pharmaceutically ac...
The present invention relates to novel heterocyclic derivatives having general formula (I) and thei...
The subject invention concerns materials and methods for inhibiting the Akt/PKB pathway. In one embo...
Targeted cancer chemotherapies hold the promise of being more selective, thus harming fewer normal c...
The present invention relates to novel piperidine derivatives having better cell growth inhibitory a...
The interest in protein kinase had been improved in recent years since the entry into the market of ...
Substituted anthranilic acid and piperazines were used as building blocks to prepare two libraries o...
Compounds of the substituted pyrazole class as treatments for cancer are reported. A method of treat...
The present invention relates to piperazinone compounds, pharmaceutical compositions containing thos...
The present invention relates to certain 4-(substituted aniline)-2-(substituted piperidin-1-yl)pyrim...
This invention relates to pyrrolopyrimidine comprising compounds that may be useful as inhibitors of...
The subject invention concerns compositions and methods for blocking cancer cell growth or prolifera...
Compounds of the general formula (I) and salts thereof are useful in the treatment of diseases assoc...
The subject invention concerns materials and methods for inhibiting the Akt/PKB pathway. In one embo...
The present invention relates to 4-pyrimidinylamino-benzenesulfonamide derivatives of general formul...
The invention provides compounds of formula (I) wherein R is −CH3 or −CH2CH3 and pharmaceutically ac...
The present invention relates to novel heterocyclic derivatives having general formula (I) and thei...
The subject invention concerns materials and methods for inhibiting the Akt/PKB pathway. In one embo...
Targeted cancer chemotherapies hold the promise of being more selective, thus harming fewer normal c...
The present invention relates to novel piperidine derivatives having better cell growth inhibitory a...
The interest in protein kinase had been improved in recent years since the entry into the market of ...
Substituted anthranilic acid and piperazines were used as building blocks to prepare two libraries o...
Compounds of the substituted pyrazole class as treatments for cancer are reported. A method of treat...
The present invention relates to piperazinone compounds, pharmaceutical compositions containing thos...