Preterm birth (<37 weeks completed weeks of gestation) affects 9 - 12% of all live births; with the majority being moderately preterm birth (32 - 36 weeks gestation). It is the leading cause of neonatal mortality and morbidity and males have been reported to be at greater risk than females. In this thesis, I have examined the effect of moderate preterm birth, using an ovine model, on the structure of the heart and cardiomyocyte growth, and on the structure and composition of the large conduit arteries (thoracic aorta and left carotid artery). Pregnant ewes were induced to deliver vaginally using epostane (50 mg in 2 ml ethanol) at 0.9 of term (132 ± 1 days of gestation) or at term (147 ± 1 days of gestation). Clinically relevant doses of Be...
Context: Preterm birth is associated with incident heart failure in children and young adults. Obje...
Advance online publication 7 February 2018Background: Globally, ∼10% of infants are born before full...
Clinically and experimentally male fetuses are at significantly greater risk of dying or suffering i...
Preterm birth (defined as birth prior to 37 completed weeks of gestation) affects 8-10% of all live ...
1. Low birth weight (LBW) is associated with an increased risk of cardiovascular disease. Preterm bi...
International audienceBACKGROUND: While hypoxic events with bradycardias are a frequent occurrence d...
Globally, 11% of infants are born preterm. In adulthood, individuals born preterm are at increased r...
Intrauterine inflammation is a major contributor to preterm birth and has adverse effects on preterm...
It is becoming increasingly clear that exposure to pregnancy complications such as hypertensive dis...
Preterm birth accounts for about 8–12% of live births in most developed countries. It is widely know...
Preterm birth affects more than 10% of births worldwide, with over 80% of these individuals born mod...
Advancements in clinical care have led to a growing cohort of preterm-born individuals now entering ...
Cardiovascular disease is a leading cause of morbidity and mortality worldwide. A large number of st...
Purpose of reviewAround 10% of the global population is born preterm (< 37 weeks’ gestation). Pre...
Clinically and experimentally male fetuses are at significantly greater risk of dying or suffering i...
Context: Preterm birth is associated with incident heart failure in children and young adults. Obje...
Advance online publication 7 February 2018Background: Globally, ∼10% of infants are born before full...
Clinically and experimentally male fetuses are at significantly greater risk of dying or suffering i...
Preterm birth (defined as birth prior to 37 completed weeks of gestation) affects 8-10% of all live ...
1. Low birth weight (LBW) is associated with an increased risk of cardiovascular disease. Preterm bi...
International audienceBACKGROUND: While hypoxic events with bradycardias are a frequent occurrence d...
Globally, 11% of infants are born preterm. In adulthood, individuals born preterm are at increased r...
Intrauterine inflammation is a major contributor to preterm birth and has adverse effects on preterm...
It is becoming increasingly clear that exposure to pregnancy complications such as hypertensive dis...
Preterm birth accounts for about 8–12% of live births in most developed countries. It is widely know...
Preterm birth affects more than 10% of births worldwide, with over 80% of these individuals born mod...
Advancements in clinical care have led to a growing cohort of preterm-born individuals now entering ...
Cardiovascular disease is a leading cause of morbidity and mortality worldwide. A large number of st...
Purpose of reviewAround 10% of the global population is born preterm (< 37 weeks’ gestation). Pre...
Clinically and experimentally male fetuses are at significantly greater risk of dying or suffering i...
Context: Preterm birth is associated with incident heart failure in children and young adults. Obje...
Advance online publication 7 February 2018Background: Globally, ∼10% of infants are born before full...
Clinically and experimentally male fetuses are at significantly greater risk of dying or suffering i...