This study was conducted to test if tumour drug uptake could be increased in experimental colorectal cancer peritoneal metastases, by using pretreatment with peritoneal vasoconstriction or radioimmunotherapy. A total of 29 nude rats with peritoneal metastases were injected intraperitoneally (i.p.) with 14C-labelled 5-FU. The animals were randomly allocated to 5 groups. Six days prior to 5-FU, group I (control) received i.p. NaCl, group II was subjected to i.p. radioimmunotherapy (RIT) 131I-labelled anti-CEA monoclonal antibody (150 MBq) and group III received i.p. Norbormide 10 minutes before 5-FU. Two days prior to 5-FU group IV and V received i.p. NaCl (control) and RIT, respectively. 5-FU uptake was visualised with autoradiography and qu...
Radioimmunotherapy using radiolabeled monoclonal antibodies (MoAbs) directed against tumor-associate...
To optimize the regional delivery advantage with i. p. administration of monoclonal antibody (mAb) ...
Objective: To investigate the role of increased intra-abdominal pressure (IAP) on the intratumoral a...
This study was conducted to test if tumour drug uptake could be increased in experimental colorectal...
Patients with peritoneal metastases from colorectal cancer have a poor prognosis. Aggressive treatme...
Although two-thirds of colorectal cancer patients are cured by surgery, approximately 50% of the pat...
Aim: This study aimed to create a peritoneal metastasis (PM) model in Wistar albino rats and nude mi...
The kinetic behavior of intraperitoneally (ip) administered proteins is poorly understood. As the ad...
PURPOSE: The aim of the study was to investigate the potential of diffusion-weighted magnetic resona...
Objectives: In our study, we aimed to (1) create a peritoneal metastasis (PM) model in nude mice, ad...
Patients with peritoneal metastases (PM) of colorectal cancer have a very poor outcome. Intraperiton...
PURPOSE: The aim of the study was to investigate the potential of diffusion-weighted magnetic resona...
Radioimmunotherapy using radiolabeled monoclonal antibodies (MoAbs) directed against tumor-associate...
To optimize the regional delivery advantage with i. p. administration of monoclonal antibody (mAb) ...
Objective: To investigate the role of increased intra-abdominal pressure (IAP) on the intratumoral a...
This study was conducted to test if tumour drug uptake could be increased in experimental colorectal...
Patients with peritoneal metastases from colorectal cancer have a poor prognosis. Aggressive treatme...
Although two-thirds of colorectal cancer patients are cured by surgery, approximately 50% of the pat...
Aim: This study aimed to create a peritoneal metastasis (PM) model in Wistar albino rats and nude mi...
The kinetic behavior of intraperitoneally (ip) administered proteins is poorly understood. As the ad...
PURPOSE: The aim of the study was to investigate the potential of diffusion-weighted magnetic resona...
Objectives: In our study, we aimed to (1) create a peritoneal metastasis (PM) model in nude mice, ad...
Patients with peritoneal metastases (PM) of colorectal cancer have a very poor outcome. Intraperiton...
PURPOSE: The aim of the study was to investigate the potential of diffusion-weighted magnetic resona...
Radioimmunotherapy using radiolabeled monoclonal antibodies (MoAbs) directed against tumor-associate...
To optimize the regional delivery advantage with i. p. administration of monoclonal antibody (mAb) ...
Objective: To investigate the role of increased intra-abdominal pressure (IAP) on the intratumoral a...