Background There is a need to prepare new nurses in disaster procedures. Virtual reality simulation (VRS) offers a method for disaster training; yet, little is known about the student experience using this type of simulation. Methods Senior baccalaureate students at two universities who experienced a VRS decontamination exercise were asked to participate in focus groups to describe their experience. Responses were analyzed using constant comparative analysis. Results Student feedback was positive, and three themes emerged from the data: The Experience of VRS, The Learning Process, and The Implementation of the Learning Activity. Conclusions VRS provides an engaging learning opportunity to learn the skill of decontamination. Educators and...