Zonulin-Dependent Intestinal Permeability in Children Diagnosed with Mental Disorders: A Systematic Review and Meta-Analysis
- Ásbjörnsdóttir, Birna Guðrún
- Snorradóttir, Heiðdís
- Andrésdóttir, Edda
- Fasano, Alessio
- Lauth, Bertrand
- Gudmundsson, Larus S
- Gottfredsson, Magnus
- Halldorsson, Thorhallur
- Birgisdottir, Bryndis Eva
DOIAbstract
Publisher's version (útgefin grein)Worldwide, up to 20% of children and adolescents experience mental disorders, which are the leading cause of disability in young people. Research shows that serum zonulin levels are associated with increased intestinal permeability (IP), affecting neural, hormonal, and immunological pathways. This systematic review and meta‐analysis aimed to summarize evidence from observational studies on IP in children diagnosed with mental disorders. The review follows the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines. A systematic search of the Cochrane Library, PsycINFO, PubMed, and the Web of Science identified 833 records. Only non‐intervention (i.e., observational) studies i...
Add to ORKG