Macroencapsulation of islets of Langerhans is a promising strategy for transplantation of insulin-producing cells in the absence of immunosuppression to treat type 1 diabetes. Hollow fiber membranes are of interest there because they offer a large surface-to-volume ratio and can potentially be retrieved or refilled. However, current available fibers have limitations in exchange of nutrients, oxygen, and delivery of insulin potentially impacting graft survival. Here, multibore hollow fibers for islets encapsulation are designed and tested. They consist of seven bores and are prepared using nondegradable polymers with high mechanical stability and low cell adhesion properties. Human islets encapsulated there have a glucose induced insulin res...
Macroencapsulation devices provide the dual possibility to immunoprotect transplanted cells while al...
Background. Microencapsulation of pancreatic islets with polymeric compounds constitutes an attracti...
Islet encapsulation in membrane-based devices could allow for transplantation of donor islet tissue ...
Macroencapsulation of islets of Langerhans is a promising strategy for transplantation of insulin-pr...
Macroencapsulation of islets of Langerhans is a promising strategy for transplantation of insulin-pr...
This work describes a route towards an immune protective device for islet of Langerhans transplantat...
Islet encapsulation devices can induce a Foreign Body Response (FBR) and the formation of a hardened...
At present, proven clinical treatments but no cures are available for diabetes, a global epidemic wi...
We have developed a replaceable bioartificial pancreas to treat diabetes utilizing a unique cocontin...
Islet transplantation for the purpose of treating insulin-dependent diabetes is currently limited by...
The number of donors required per recipient and the associated immunosuppressive regimen are the maj...
Stem cell derived insulin producing cells or islets have shown promise in reversing Type 1 Diabetes ...
Contains fulltext : 177862.pdf (publisher's version ) (Open Access)Allogeneic isle...
Macroencapsulation devices provide the dual possibility to immunoprotect transplanted cells while al...
Background. Microencapsulation of pancreatic islets with polymeric compounds constitutes an attracti...
Islet encapsulation in membrane-based devices could allow for transplantation of donor islet tissue ...
Macroencapsulation of islets of Langerhans is a promising strategy for transplantation of insulin-pr...
Macroencapsulation of islets of Langerhans is a promising strategy for transplantation of insulin-pr...
This work describes a route towards an immune protective device for islet of Langerhans transplantat...
Islet encapsulation devices can induce a Foreign Body Response (FBR) and the formation of a hardened...
At present, proven clinical treatments but no cures are available for diabetes, a global epidemic wi...
We have developed a replaceable bioartificial pancreas to treat diabetes utilizing a unique cocontin...
Islet transplantation for the purpose of treating insulin-dependent diabetes is currently limited by...
The number of donors required per recipient and the associated immunosuppressive regimen are the maj...
Stem cell derived insulin producing cells or islets have shown promise in reversing Type 1 Diabetes ...
Contains fulltext : 177862.pdf (publisher's version ) (Open Access)Allogeneic isle...
Macroencapsulation devices provide the dual possibility to immunoprotect transplanted cells while al...
Background. Microencapsulation of pancreatic islets with polymeric compounds constitutes an attracti...
Islet encapsulation in membrane-based devices could allow for transplantation of donor islet tissue ...