Osteoporos Int

Background:There are limited data on demographic and body size relationships for trabecular bone score (TBS), a new approach to assess bone microarchitecture.Purpose:Compare demographic patterns and correlations with body size (body mass index (BMI), weight, waist circumference, total body fat, trunk fat, trunk lean) between TBS and lumbar spine bone mineral density (LSBMD) for adults age 65 20 years from the National Health and Nutrition Examination Survey (NHANES) 2005\u20132008 with BMI in the optimal range for TBS (15\u201337 kg/m2).Methods:LSBMD, TBS, body fat and lean were obtained by dual-energy X-ray absorptiometry. Weight, height and waist circumference were measured. BMI was calculated from height and weight.Results:Sex differences in TBS varied by age and race/ethnicity (psex X age interaction and psex X race/ethnicity interaction NHW>MA). All body size variables were negatively related to TBS but positively related to LSBMD.Conclusion:Demographic patterns and body size relationships differed between TBS and LSBMD. In some cases, they identified different at-risk subgroups (subgroup with lowest values).Mini-abstractThis study examines demographic patterns and body size relationships in trabecular bone score and lumbar spine BMD of US adults from NHANES 2005\u20132008.CC999999/ImCDC/Intramural CDC HHS/United States2020-10-29T00:00:00Z26952009PMC7593898858