Int J Environ Res Public Health

Thousands of lower Manhattan residents sustained damage to their homes following the collapse of the Twin Towers on 11 September 2001. Respiratory outcomes have been reported in this population. We sought to describe patterns of home damage and cleaning practices in lower Manhattan and their impacts on respiratory outcomes among World Trade Center Health Registry (WTCHR) respondents. Data were derived from WTCHR Wave 1 (W1) (9/2003\u207b11/2004) and Wave 2 (W2) (11/2006\u207b12/2007) surveys. Outcomes of interest were respiratory symptoms (shortness of breath (SoB), wheezing, persistent chronic cough, upper respiratory symptoms (URS)) first occurring or worsening after 9/11 W1 and still present at W2 and respiratory diseases (asthma and chronic obstructive pulmonary disease (COPD)) first diagnosed after 9/11 W1 and present at W2. We performed descriptive statistics, multivariate logistic regression and geospatial analyses, controlling for demographics and other exposure variables. A total of 6447 residents were included. Mean age on 9/11 was 45.1 years (\ub115.1 years), 42% were male, 45% had ever smoked cigarettes, and 44% reported some or intense dust cloud exposure on 9/11. The presence of debris was associated with chronic cough (adjusted OR (aOR) = 1.56, CI: 1.12\u207b2.17), and upper respiratory symptoms (aOR = 1.56, CI: 1.24\u207b1.95). A heavy coating of dust was associated with increased shortness of breath (aOR = 1.65, CI: 1.24\u207b2.18), wheezing (aOR = 1.43, CI: 1.03\u207b1.97), and chronic cough (aOR = 1.59, CI: 1.09\u207b2.28). Dusting or sweeping without water was the cleaning behavior associated with the largest number of respiratory outcomes, such as shortness of breath, wheezing, and URS. Lower Manhattan residents who suffered home damage following the 9/11 attacks were more likely to report respiratory symptoms and diseases compared to those who did not report home damage.U50 OH009739/OH/NIOSH CDC HHS/United StatesU50/ATU272750/CC/CDC HHS/United States30841531PMC6427564809