Activated platelets release a multifaceted blend of growth factors that has stimulatory effects on mesenchymal cells, both in vitro and in vivo, which imply beneficial effects on wound repair and tissue regeneration. Previous studies on fibroblast cultures have revealed that more potent growth factors, with respect to cell proliferation, are released in acidic preparations of lysed platelet concentrates in comparison with neutral and alkaline preparations. The current study was intended to investigate the influence of pH on lysed platelet concentrates with respect to release of growth factors, cell proliferation and alkaline phosphatase (ALP) activity in human osteoblast-like cells (hFOB 1.19). Cell proliferation was assessed with the MTT k...
Background Human platelet lysate (HPL) is emerging as the preferred xeno-free supplement for the exp...
AIM: Platelet rich plasma (PRP) is utilized in oral surgery to enhance bone healing and it has b...
Studies on new procedures for bone reconstruction suggest that autologous cells seeded on a resorbab...
BACKGROUND AND PURPOSE: Growth factors released from platelets have potent effects on fracture and w...
latelets contain numerous growth factors essential for wound and fracture healing. We investigated t...
BACKGROUND AIMS: An extensive debate about the clinical benefits of autologous platelet concentrate...
We investigated the effects of alkaline pH on developing osteoblasts. Cells of the osteoblast-like c...
Tissue healing is a complex process involving several players such as cells and growth factors relea...
Tissue healing is a complex process involving several players such as cells and growth factors relea...
Variation of pH in lysed platelet concentrates influence proliferation and alkaline phosphatase acti...
Platelet Lysate (PL) contains a cocktail of growth factors and cytokines, which actively participate...
International audienceActivated platelet concentrates are autologous blood preparations containing s...
The present study aimed at elucidating the effect of local pH in the extracellular microenvironment ...
International audienceThe present study aimed at elucidating the effect of local pH in the extracell...
Despite wide clinical application, the efficacy of platelet-rich plasma (PRP) for repairing bone def...
Background Human platelet lysate (HPL) is emerging as the preferred xeno-free supplement for the exp...
AIM: Platelet rich plasma (PRP) is utilized in oral surgery to enhance bone healing and it has b...
Studies on new procedures for bone reconstruction suggest that autologous cells seeded on a resorbab...
BACKGROUND AND PURPOSE: Growth factors released from platelets have potent effects on fracture and w...
latelets contain numerous growth factors essential for wound and fracture healing. We investigated t...
BACKGROUND AIMS: An extensive debate about the clinical benefits of autologous platelet concentrate...
We investigated the effects of alkaline pH on developing osteoblasts. Cells of the osteoblast-like c...
Tissue healing is a complex process involving several players such as cells and growth factors relea...
Tissue healing is a complex process involving several players such as cells and growth factors relea...
Variation of pH in lysed platelet concentrates influence proliferation and alkaline phosphatase acti...
Platelet Lysate (PL) contains a cocktail of growth factors and cytokines, which actively participate...
International audienceActivated platelet concentrates are autologous blood preparations containing s...
The present study aimed at elucidating the effect of local pH in the extracellular microenvironment ...
International audienceThe present study aimed at elucidating the effect of local pH in the extracell...
Despite wide clinical application, the efficacy of platelet-rich plasma (PRP) for repairing bone def...
Background Human platelet lysate (HPL) is emerging as the preferred xeno-free supplement for the exp...
AIM: Platelet rich plasma (PRP) is utilized in oral surgery to enhance bone healing and it has b...
Studies on new procedures for bone reconstruction suggest that autologous cells seeded on a resorbab...