miRNAs-Directed Signaling in Lung Transplantation Reveals Differential Transcription Factors Expression in Acute or Chronic Lung Dysfunction
- V. Vaira
- A. Palleschi
- G. Gaudioso
- V. Edefonti
- V. Musso
- A. Terrasi
- F. Ambrogi
- L. Morlacchi
- L. Rosso
- D. Tosi
- S. Franzi
- S. Ferrero
- M. Nosotti
DOIAbstract
In a previous study on miRNA profiling in bronchoalveolar lavage (BAL) fluid of lung transplanted (LTx) patients we obtained signatures of deregulated miRNAs associated to acute lung allograft dysfunction (ALAD). Now we extended this analysis to chronic dysfunction (CLAD) and to pathways potentially modulated by AR- or CLAD-miRNAs
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