Prevalence of Frailty in Brazilian Older Adults : a Systematic Review and Meta-Analysis

Objectives: Frailty is characterized by a functioning decline in multiple systems accompanied by an increase in individual\u2019s vulnerability to stressors. It appears to be higher in low and middle-income countries compared with high-income ones. This study aimed to evaluate the prevalence of frailty in non-institutionalized Brazilian older adults. Design: a systematic review and meta-analysis study. Setting: Cross-sectional and prospective data from Brazil. Participants: non-institutionalized adults aged 60 and older. Methods: Electronic searches were performed in PubMed/MEDLINE, LILACS, SCOPUS and Web of Science, considering the studies published between March 2001 and July 2018, using a combination of the following terms and correlates: \u201celder\u201d AND \u201cfrail\u201d AND \u201cprevalence\u201d AND \u201cBrazil\u201d. Two independent reviewers selected studies according to the inclusion criteria. Disagreements were resolved by a third reviewer (title/abstract) and by consensus. Studies with samples 65221 subjects were considered for meta-analysis. Results: 28 studies were included, while 18 had the data meta-analyzed. The majority of studies (61%) included older adults only from the Southeastern region. The number of subjects ranged from 53 to 5,532 individuals (N = 17,604) and the average age ranged from 65.6 to 85.5 years. The overall prevalence of frailty was 24%. When considering the different assessment methods, the prevalence was lower for frailty phenotype (16%) compared with other criteria (40%). Regarding sex, the prevalence of frailty was similar for women (28%) and men (25%). The prevalence of frailty was higher in older adults recruited from health care services (30%) compared to community ones (22%). Conclusion: In Brazil, the overall prevalence of frailty in non-institutionalized older adults is higher than observed from more developed countries. However, it may vary according to the assessment methods and settings