Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study : Analysis of 36-month observational data
- Tabrizi, Sarah
- Scahill, Rachael
- Owen, Gail
- Durr, Alexandra
- Leavitt, Blair
- Roos, Raymund
- Borowsky, Beth
- Landwehrmeyer, Bernhard
- Frost, Chris
- Johnson, Hans
- Craufurd, David
- Reilmann, Ralf
- Stout, Julie
- Langbehn, Douglas
DOIAbstract
Background: TRACK-HD is a multinational prospective observational study of Huntington's disease (HD) that examines clinical and biological findings of disease progression in individuals with premanifest HD (preHD) and early-stage HD. We aimed to describe phenotypic changes in these participants over 36 months and identify baseline predictors of progression
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