Sphingolipids are important signalling molecules and thus it is very important to understand how they are generated. Sphingolipid biosynthesis shows a conserved compartmentalization in eukaryotic cells. Their synthesis begins in the endoplasmic reticulum and is completed in the Golgi apparatus. We now know quite a bit about the topology of the reactions in the pathway, but certain critical steps, such as ceramide synthesis, are still poorly understood. In the present paper, we discuss the latest views on this subject
In animals, plants, and fungi, the specific complex sphingolipids are generated in the Golgi by diff...
In yeast, the long-chain sphingoid base phosphate phosphohydrolase Lcb3p is required for efficient c...
International audienceLong chain sphingoid bases (LCBs) and their phosphates (LCBPs) are not only im...
Sphingolipids are ubiquitous components of eukaryotic cell membranes, where they play important role...
AbstractUnlike the synthesis of other membrane lipids, sphingolipid synthesis is compartmentalized b...
Although the yeast Saccharomyces cerevisiae has only one sphingolipid class with a head group based ...
Summary: Sphingolipid biosynthesis occurs in both the endoplasmic reticulum (ER) and the Golgi appar...
AbstractUnlike the synthesis of other membrane lipids, sphingolipid synthesis is compartmentalized b...
Sphingolipids are the most diverse class of membrane lipids, in terms of their structure and functio...
Ceramide plays a crucial role as a basic building block of sphingo-lipids, but also as a signalling ...
Sphingolipids constitute a class of lipid compounds which carry out important structural and signali...
Ceramides are bioactive lipids and precursors to sph-ingolipids. They have been shown to take part i...
<p>Schematic overview of yeast sphingolipid metabolism displaying the metabolic intermediates, genes...
Sphingolipids constitute a class of lipids defined by their eighteen carbon amino-alcohol backbones ...
Sphingolipids are abundant components of eukaryotic cells. Their localization in the plasma membrane...
In animals, plants, and fungi, the specific complex sphingolipids are generated in the Golgi by diff...
In yeast, the long-chain sphingoid base phosphate phosphohydrolase Lcb3p is required for efficient c...
International audienceLong chain sphingoid bases (LCBs) and their phosphates (LCBPs) are not only im...
Sphingolipids are ubiquitous components of eukaryotic cell membranes, where they play important role...
AbstractUnlike the synthesis of other membrane lipids, sphingolipid synthesis is compartmentalized b...
Although the yeast Saccharomyces cerevisiae has only one sphingolipid class with a head group based ...
Summary: Sphingolipid biosynthesis occurs in both the endoplasmic reticulum (ER) and the Golgi appar...
AbstractUnlike the synthesis of other membrane lipids, sphingolipid synthesis is compartmentalized b...
Sphingolipids are the most diverse class of membrane lipids, in terms of their structure and functio...
Ceramide plays a crucial role as a basic building block of sphingo-lipids, but also as a signalling ...
Sphingolipids constitute a class of lipid compounds which carry out important structural and signali...
Ceramides are bioactive lipids and precursors to sph-ingolipids. They have been shown to take part i...
<p>Schematic overview of yeast sphingolipid metabolism displaying the metabolic intermediates, genes...
Sphingolipids constitute a class of lipids defined by their eighteen carbon amino-alcohol backbones ...
Sphingolipids are abundant components of eukaryotic cells. Their localization in the plasma membrane...
In animals, plants, and fungi, the specific complex sphingolipids are generated in the Golgi by diff...
In yeast, the long-chain sphingoid base phosphate phosphohydrolase Lcb3p is required for efficient c...
International audienceLong chain sphingoid bases (LCBs) and their phosphates (LCBPs) are not only im...