Sensitive detection of SARS-CoV-2-specific antibodies in dried blood spot samples
- Morley, Gabriella L
- Jossi, Sian
- Perez-Toledo, Marisol
- Faustini, Sian E
- Marcial-Juarez, Edith
- Shields, Adrian M
- Goodall, Margaret
- Allen, Joel D
- Watanabe, Yasunori
- Newby, Maddy L
- Crispin, Max
- Drayson, Mark T
- Cunningham, Adam F
- Richter, Alex G
- O'Shea, Matthew K
Publication date
December 2020
DOI Publisher
Centers for Disease Control and Prevention (CDC)Abstract
Dried blood spot (DBS) samples can be used for the detection of severe acute respiratory syndrome coronavirus 2 spike antibodies. DBS sampling is comparable to matched serum samples with a relative 98.1% sensitivity and 100% specificity. Thus, DBS sampling offers an alternative for population-wide serologic testing in the coronavirus pandemic.</p
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