Oxachamigrenes, new halogenated sesquiterpenes from Laurencia obtusa

3 pages, 3 figures, 1 table.-- PMID: 12088448 [PubMed].-- Printed version published Jun 28, 2002.Supporting information (2 pages) available at: http://pubs.acs.org/doi/suppl/10.1021/np010580tTwo new sesquiterpenes belonging to a novel oxacyclic structural type of chamigrene skeleton, oxachamigrene (1) and 5-acetoxyoxachamigrene (2), have been isolated from the red alga Laurencia obtusa. The structures of the compounds were determined on the basis of spectroscopic evidence. A biogenetic route for these metabolites has been proposed.This work was supported by Ministerio de Ciencia y Tecnología (MCYT), FEDER (project 1FD97-0348- C03-03), Subdirección General de Cooperación Internacional, Program of Cooperation between the Consejo Superior de Investigaciones Científicas (CSIC, Spain)-Universidad de Chile and the collaboration of CEBIMAR of Cuba. I.B. acknowledges a grant from the CICYT