Antioxidant activity and flavonoid derivatives of Plumbago zeylanica

ABSTRACT Plumbago zeylanica (Chitrak) is a useful Indian medicinal plant. The root of the plant and its constituents are credited with potential therapeutic properties. The isolation and spectral data for new flavonoid 2-(2, 4-Dihydroxy-phenyl)-3, 6, 8-trihydroxy-chromen-4-one from the roots of Plumbago zeylanica were determined and the antioxidant activity were studied by free radical scavenging and superoxide radical scavenging assays. The plant roots extract reveled significant antioxidant activity as compared to standard flavonoid (quercetin). The antioxidant activity by DPPH is 96µg/ml and by NBT is 4.6µg/ml which grater than that of standard (Quercetin) 45 µg/ml by DPPH and 10µg/ml by NBT assay. The phytochemical investigation showed presence of flavonoids, tannins and saponins. The total phenolic and total flavonoid content was found to be 260±48.0 and 45.5±5.2 mg of GAE/g and CE/g respectively