PoiNt-of-View An effort to make sense of antisense transcription in bacteria

Pervasive Overlapping Transcription in Bacteria Implementation of high-throughput RNA analysis techniques to the identification of the entire collection of RNA molecules (transcriptome) produced by a bacterial population has directed our view of RNA landscapes away from a protein-centric genome annotation. As with studies involving eukaryotic cells, the first bacterial transcriptomic studies also revealed the existence of a genome-wide process of overlapping transcription