Abstract Wnts are a family of signaling glycoproteins which play essential roles in many developmental processes and adult homeostasis. Misregulated Wnt signaling has been implicated in a variety of human diseases including cancers. The tight regulation of Wnt signaling is not only reflected by the diverse responses triggered in the Wnt-receiving cells, but also, as more recent work suggested, by the complex control on Wnt processing, secretion, and subsequent distribution. The characterization of the nature and roles of posttranslational modifications of Wnt molecules and the discovery of Wntless (Wls) and the retromer complex as novel and indispensable players in Wnt release have led to closer inspection of the Wnt secretory routes. Moreo...
Signaling pathways function as molecular instruments mediating cellular response to intrinsic and ex...
SummarySecreted Wnt proteins play essential roles in many biological processes during development an...
Wnts are a family of secreted palmitoleated glycoproteins that play key roles in cell to cell commun...
Wnts are highly-conserved lipid-modified secreted proteins that activate multiple signaling pathways...
Wnts are secreted glycolipoproteins fundamental for embryonic development and adult tissue homeostas...
The Wnt pathway is a key morphogen route during embryonic development, regulating tissue organizatio...
Cell to cell communication is essential during development of all animals. Several intercellular com...
Wnt signalling, a key pathway involved in various aspects of embryonic development, also underlies m...
Wnt proteins comprise one family of secreted signaling molecules that is conserved in a wide range o...
Selva, Erica M.Wnt proteins are a highly conserved family of secreted glycoproteins that act as liga...
The Wnt pathway is central to a host of developmental and disease-related processes. The remarkable ...
The Wnt family of signaling proteins has essential functions in development and adult tissue homeost...
How functional WNT proteins are made and how their secretion is regulated is becoming a focal point ...
Selva, Erica M.Wnt signal transduction plays important roles in numerous phases of organismal develo...
SummaryWnt proteins are secreted signaling molecules that play a central role in development and adu...
Signaling pathways function as molecular instruments mediating cellular response to intrinsic and ex...
SummarySecreted Wnt proteins play essential roles in many biological processes during development an...
Wnts are a family of secreted palmitoleated glycoproteins that play key roles in cell to cell commun...
Wnts are highly-conserved lipid-modified secreted proteins that activate multiple signaling pathways...
Wnts are secreted glycolipoproteins fundamental for embryonic development and adult tissue homeostas...
The Wnt pathway is a key morphogen route during embryonic development, regulating tissue organizatio...
Cell to cell communication is essential during development of all animals. Several intercellular com...
Wnt signalling, a key pathway involved in various aspects of embryonic development, also underlies m...
Wnt proteins comprise one family of secreted signaling molecules that is conserved in a wide range o...
Selva, Erica M.Wnt proteins are a highly conserved family of secreted glycoproteins that act as liga...
The Wnt pathway is central to a host of developmental and disease-related processes. The remarkable ...
The Wnt family of signaling proteins has essential functions in development and adult tissue homeost...
How functional WNT proteins are made and how their secretion is regulated is becoming a focal point ...
Selva, Erica M.Wnt signal transduction plays important roles in numerous phases of organismal develo...
SummaryWnt proteins are secreted signaling molecules that play a central role in development and adu...
Signaling pathways function as molecular instruments mediating cellular response to intrinsic and ex...
SummarySecreted Wnt proteins play essential roles in many biological processes during development an...
Wnts are a family of secreted palmitoleated glycoproteins that play key roles in cell to cell commun...