Mycobacterial lipoarabinomannan affects human polymorphonuclear and mononuclear phagocyte functions differently

Background and Objectives. The role of mycobacterial lipoarabinomannan (LAM) in regulating the granulomatous response and its effects on cells involved in early responses to tuberculosis have not been clearly defined. The aim of this study was to acquire further evidence about the mechanisms by which LAM takes part in the host response to mycobacterial infections