Effect of increasing load exhaustive exercise on oxidative stress of skeletal muscle in different parts of rat

Abstract: To explore oxidative stress condition of skeletal muscle in different parts of rat under the influence of the increasing load exhaustive exercise. Divide the 7-week-old SD male rats into two groups: quiet group(CG) and exhaustion group (EG). Conduct this experiment on the exhaustive group by gradually increasing load to skeletal muscle cells until exhaustive exercise and detect skeletal muscle cells' oxidative stress change.Quadriceps and gastrocnemius muscles' antioxidant activity increased, MDA content decreased, of which quadriceps CAT, GSH-PX activity increased more significantly(P<0.05) after gradually increasing load exhaustive exercise; in contrast, flounder's antioxidant enzyme activity decreased, MDA content increased.Gradually increasing load exhaustive exercise can lead to oxidative damage of flounder muscle