Cinnamon aqueous extract ameliorates deltamethrin-induced

ABSTRACT The present work studied the effect of cinnamon aqueous extract on hepatic injury induced by the pyrethroid insecticide, deltamethrin, in albino rats. Treating animals with deltamethrin at a dose level of 1 / 10 LD 50 , 3 days weekly for 6 weeks caused biochemical and histological alterations. Biochemical results revealed significant increase in serum level of ALT, AST and ALP, and decrease in total proteins. Examination of liver sections stained with H&E showed loss of normal structure of the hepatic cells, blood congestion, leucocytic infiltration, cytoplasmic vacuolation of the hepatocytes and fatty degeneration. Treating animals with deltamethrin and cinnamon revealed an improvement in the biochemical and histological changes observed in animals treated with deltamethrin. This effect of cinnamon extract may be attributed to its antioxidant activity