Abstract Mathematical analysis of absorption spectra of biologically active substances is presented. Two models of interactions of mutagen and caffeine with DNA analyzed and obtained binding parameters show good coincidence. Using different models, which take into account formation of various complexes, it is possible to calculate different binding parameters of such triple systems and choose the model describing corresponding system in the best way
Author Institution: Department of Chemistry, Faculty of Science, UAE University,; Al-Ain P.O. Box 17...
Traditional analysis of drug binding data relies upon the Scatch and formalism. These methods rely u...
DNA is one of the major intracellular targets for a wide range of anticancer and antibiotic drugs. E...
Recent studies have demonstrated that caffeine can act as an antimutagen and inhibit the cytoxic and...
Nucleic acids exist in a dynamic equilibrium with a number of molecules that constantly interact wit...
Nucleic acids exist in a dynamic equilibrium with a number of molecules that constantly interact wit...
<p>(<b>A</b>). The percentage of hyperchromicity with respect P/D 6, 3, 1 and 0.8 of theophylline (X...
1H NMR spectroscopy (500 MHz) has been used to quantify the complexation of the antibacterial antibi...
<p>(<b>A</b>). Ultraviolet absorption spectrum of DNA in the presence of 10 mM Mg<sup>2+</sup>. (<b>...
AbstractThe interaction between thiabendazole (TBZ) and calf-thymus DNA (ct-DNA) was studied by expe...
Interaction of naturally occurring bioactive flavonoids 5,6,7-trihydroxyflavone (Baicalein) and 7,8-...
In the present work pharmacodynamic interactions of thirteen antineoplastic drugs with DNA were inve...
This unit serves as a starting point for exploring the thermodynamic properties of interactions betw...
A large number of inorganic and organic compounds is able to bind to DNA and form complexes. Among t...
AbstractPorphyrins and metalloporphyrins are strong DNA binders. Some of these compounds have been u...
Author Institution: Department of Chemistry, Faculty of Science, UAE University,; Al-Ain P.O. Box 17...
Traditional analysis of drug binding data relies upon the Scatch and formalism. These methods rely u...
DNA is one of the major intracellular targets for a wide range of anticancer and antibiotic drugs. E...
Recent studies have demonstrated that caffeine can act as an antimutagen and inhibit the cytoxic and...
Nucleic acids exist in a dynamic equilibrium with a number of molecules that constantly interact wit...
Nucleic acids exist in a dynamic equilibrium with a number of molecules that constantly interact wit...
<p>(<b>A</b>). The percentage of hyperchromicity with respect P/D 6, 3, 1 and 0.8 of theophylline (X...
1H NMR spectroscopy (500 MHz) has been used to quantify the complexation of the antibacterial antibi...
<p>(<b>A</b>). Ultraviolet absorption spectrum of DNA in the presence of 10 mM Mg<sup>2+</sup>. (<b>...
AbstractThe interaction between thiabendazole (TBZ) and calf-thymus DNA (ct-DNA) was studied by expe...
Interaction of naturally occurring bioactive flavonoids 5,6,7-trihydroxyflavone (Baicalein) and 7,8-...
In the present work pharmacodynamic interactions of thirteen antineoplastic drugs with DNA were inve...
This unit serves as a starting point for exploring the thermodynamic properties of interactions betw...
A large number of inorganic and organic compounds is able to bind to DNA and form complexes. Among t...
AbstractPorphyrins and metalloporphyrins are strong DNA binders. Some of these compounds have been u...
Author Institution: Department of Chemistry, Faculty of Science, UAE University,; Al-Ain P.O. Box 17...
Traditional analysis of drug binding data relies upon the Scatch and formalism. These methods rely u...
DNA is one of the major intracellular targets for a wide range of anticancer and antibiotic drugs. E...