Influence of composition on the in-vitro bioactivity of bioglass prepared by a quick alkali-mediated sol-gel method

Abstract: Bioactive glass with composition SiO 2 , Na 2 O, CaO, P 2 O 5 with MgO additive were synthesized through a quick alkali mediated sol-gel method. MgO was substituted for SiO 2 in glass formula up to 5 wt% and in-vitro bioactivity of the samples (precipitation behavior of carbonated apatite likely bone layer) was evaluated by soaking them in simulated body fluid (SBF). The characterizations were carried out using XRD, FT-IR, TGA, and DSC. The thermal results showed that all organic and inorganic precursors were completely decomposed before 600 °C and, hence, all glass samples were stabilized at this temperature. The results obtained showed that MgO doping to glass samples increased its degradation and the formation of apatite like bone is delayed