Add to ORKGOne hundred years after Weismann's seminal observations, the mechanisms that distinguish the germline from the soma still remain poorly understood. This review describes recent studies in Caenorhabditis elegans, which suggest that germ cells utilize unique mechanisms to regulate gene expression. In particular, mechanisms that repress the production of mRNAs appear to be essential to maintain germ cell fate and viability
Adult tissue maintenance is achieved through a tightly controlled equilibrium of 2 opposing cell fat...
International audienceCaenorhabditis elegans early embryos generate cell-specific transcriptomes des...
International audienceCaenorhabditis elegans early embryos generate cell-specific transcriptomes des...
Translational control is a prevalent form of gene expression regulation in the Caenorhabditis elegan...
Abstract Translational control is a prevalent form of gene expression regulation in the Caenorhabdit...
Cell-cell interactions control many cell fate choices during the development of multicellular organi...
Cell-cell interactions control many cell fate choices during the development of multicellular organi...
SummaryGene regulation often plays by different rules in the germline compared to the soma. In Caeno...
Abstract A central feature of the continuum of life in sexually reproducing metazoans is the cycle o...
AbstractTranscription is globally silenced in the germline of animals. Recent studies have shown tha...
Background: Germ cells must progress through elaborate developmental stages from an...
Abstract The C. elegans germ line has emerged as an important model for understanding how a stem cel...
SummaryHow genes are regulated to produce the correct assortment of proteins for every cell type is ...
The potential of a cell to produce all types of differentiated cells in an organism is termed totipo...
The potential of a cell to produce all types of differentiated cells in an organism is termed totipo...
Adult tissue maintenance is achieved through a tightly controlled equilibrium of 2 opposing cell fat...
International audienceCaenorhabditis elegans early embryos generate cell-specific transcriptomes des...
International audienceCaenorhabditis elegans early embryos generate cell-specific transcriptomes des...
Translational control is a prevalent form of gene expression regulation in the Caenorhabditis elegan...
Abstract Translational control is a prevalent form of gene expression regulation in the Caenorhabdit...
Cell-cell interactions control many cell fate choices during the development of multicellular organi...
Cell-cell interactions control many cell fate choices during the development of multicellular organi...
SummaryGene regulation often plays by different rules in the germline compared to the soma. In Caeno...
Abstract A central feature of the continuum of life in sexually reproducing metazoans is the cycle o...
AbstractTranscription is globally silenced in the germline of animals. Recent studies have shown tha...
Background: Germ cells must progress through elaborate developmental stages from an...
Abstract The C. elegans germ line has emerged as an important model for understanding how a stem cel...
SummaryHow genes are regulated to produce the correct assortment of proteins for every cell type is ...
The potential of a cell to produce all types of differentiated cells in an organism is termed totipo...
The potential of a cell to produce all types of differentiated cells in an organism is termed totipo...
Adult tissue maintenance is achieved through a tightly controlled equilibrium of 2 opposing cell fat...
International audienceCaenorhabditis elegans early embryos generate cell-specific transcriptomes des...
International audienceCaenorhabditis elegans early embryos generate cell-specific transcriptomes des...