ABSTRACT High-dose methamphetamine (METH) causes damage to the dopamine and serotonin neurons in the brains of laboratory animals. The purpose of this report was to determine the longterm consequences of high-dose METH treatment on behavior and neurochemistry. Rats were trained on the differential reinforcement of low-rate 72-s (DRL 72-s) schedule of reinforcement. Twelve weeks after training began (age 23 weeks), they received one or three high-dose METH regimens. Each regimen consisted of four injections of 15 mg/kg, at 2-h intervals. Each regimen was separated by 7 weeks. A second group received METH treatment at age 23 weeks, but behavioral training was not initiated until the rats reached age 60 weeks. A third group received METH treat...
This study investigated the acute effect of a dose range of low-to-moderate binge-like methamphetami...
In recent work we have documented lasting adverse neurochemical and behavioural effects in rats give...
dissertationThe effects of multiple toxic doses of methamphetamine on catecholaminergic, serotonergi...
Brain neurochemistry and cognition performance are thought to decline with age. Accumulating data in...
Methamphetamine (METH) abuse is known to induce persistent cognitive and behavioral abnormalities, i...
METH is known to produce neurotoxic effects in the central nervous system, affecting an array of beh...
MSc (Pharmacology), North-West University, Potchefstroom Campus, 2014Methamphetamine (MA) is a well-...
[eng] A recent study from our laboratory demonstrated that binge methamphetamine induced hippocampal...
Thesis (MSc (Pharmacology))--North-West University, Potchefstroom Campus, 2013.Methamphetamine (MA) ...
Drug use among adolescents continues to be an area of concern because of the possibility of long-las...
Chronic methamphetamine (MA) abuse results in an acute psychosis indistinguishable from paranoid sch...
Different methamphetamine use patterns in human subjects may contribute to inconsistent findings reg...
Studies have demonstrated that AMPHs produce long-term damage to the brain dopaminergic, serotoniner...
Methamphetamine, an amphetamine derivative, is a powerful psychomotor stimulant and commonly used dr...
Mephedrone (4-methylmethcathinone, MMC) is a popular recreational drug, yet its potential harms are ...
This study investigated the acute effect of a dose range of low-to-moderate binge-like methamphetami...
In recent work we have documented lasting adverse neurochemical and behavioural effects in rats give...
dissertationThe effects of multiple toxic doses of methamphetamine on catecholaminergic, serotonergi...
Brain neurochemistry and cognition performance are thought to decline with age. Accumulating data in...
Methamphetamine (METH) abuse is known to induce persistent cognitive and behavioral abnormalities, i...
METH is known to produce neurotoxic effects in the central nervous system, affecting an array of beh...
MSc (Pharmacology), North-West University, Potchefstroom Campus, 2014Methamphetamine (MA) is a well-...
[eng] A recent study from our laboratory demonstrated that binge methamphetamine induced hippocampal...
Thesis (MSc (Pharmacology))--North-West University, Potchefstroom Campus, 2013.Methamphetamine (MA) ...
Drug use among adolescents continues to be an area of concern because of the possibility of long-las...
Chronic methamphetamine (MA) abuse results in an acute psychosis indistinguishable from paranoid sch...
Different methamphetamine use patterns in human subjects may contribute to inconsistent findings reg...
Studies have demonstrated that AMPHs produce long-term damage to the brain dopaminergic, serotoniner...
Methamphetamine, an amphetamine derivative, is a powerful psychomotor stimulant and commonly used dr...
Mephedrone (4-methylmethcathinone, MMC) is a popular recreational drug, yet its potential harms are ...
This study investigated the acute effect of a dose range of low-to-moderate binge-like methamphetami...
In recent work we have documented lasting adverse neurochemical and behavioural effects in rats give...
dissertationThe effects of multiple toxic doses of methamphetamine on catecholaminergic, serotonergi...