2003-222.aug

P e r s o n a l n o n -c o m m e r c i a l u s e o n l y . T h e J o u r n a l o f R h e u m a t o l o g y . C o p y r i g h t © 2 0 0 4 . A l l r i g h t s r e s e r v e d Systemic lupus erythematosus (SLE) is a chronic disease with considerable heterogeneity and an unpredictable course. In recent years, patient management through dietary manipulation has received attention Limited research into the effect of fish oils in humans with SLE has on the whole revealed favorable improvement in disease activity We report the effects of daily dietary supplementation ABSTRACT. Objective. To determine the effect of dietary supplementation with omega-3 fish oils with or without copper on disease activity in systemic lupus erythematosus (SLE). Fish oil supplementation has a beneficial effect on murine models of SLE, while exogenous copper can decrease the formation of lupus erythematosus cells in rats with a hydralazine-induced collagen disease