Abstract Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) affecting deer (Odocoileus spp.), moose (Alces alces), and Rocky Mountain elk (Cervus elaphus nelsoni). Leucine homozygosity at elk PRNP codon 132 has been associated with reduced CWD susceptibility. However, naturally acquired CWD has been detected in elk possessing the 132 Leu/Leu genotype. Recent human and bovine studies indicate that PRNP regulatory polymorphisms may also influence TSE occurrence. Therefore, we generated sequences for the elk PRNP putative promoter (2.2 kb), exon 1 (predicted; 54 bp), intron 1 (predicted; 193 bp), and exon 3 (771 bp). Promoter prediction analysis using CpGProD yielded a single elk PRNP promoter that was homologous ...
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) that affects member...
The PrP gene encodes the putative causative agent of the transmissible spongiform encepha-lopathies ...
AbstractUntil recently, chronic wasting disease of cervids, the only prion disease affecting wildlif...
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) affecting deer (Odo...
© 2008 American Genetic AssociationChronic wasting disease (CWD) is a transmissible spongiform encep...
Background: Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) of cerv...
Abstract Background Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE)...
The PrP gene encodes the putative causative agent of the transmissible spongiform encephalopathies (...
PRNP genotypes, number of octarepeats (PHGGGWGQ) and indels in the PRNP promoter can influence the p...
To compare the genetic susceptibility of elk (Cervus elaphus nelsoni) with various alleles of the PR...
Abstract Background The Rocky Mountain elk (Cervus elaphus nelsoni) prion protein gene (PRNP) is pol...
Pathogenesis and transmission of the prion disorders (transmissible spongiform encephalopathies, TSE...
The sequence of the prion protein gene (PRNP) affects susceptibility to spongiform encephalopathies,...
Chronic Wasting Disease (CWD) is a contagious prion disease affecting various species of free-rangin...
The first European cases of chronic wasting disease (CWD) in free-ranging reindeer and wild elk were...
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) that affects member...
The PrP gene encodes the putative causative agent of the transmissible spongiform encepha-lopathies ...
AbstractUntil recently, chronic wasting disease of cervids, the only prion disease affecting wildlif...
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) affecting deer (Odo...
© 2008 American Genetic AssociationChronic wasting disease (CWD) is a transmissible spongiform encep...
Background: Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) of cerv...
Abstract Background Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE)...
The PrP gene encodes the putative causative agent of the transmissible spongiform encephalopathies (...
PRNP genotypes, number of octarepeats (PHGGGWGQ) and indels in the PRNP promoter can influence the p...
To compare the genetic susceptibility of elk (Cervus elaphus nelsoni) with various alleles of the PR...
Abstract Background The Rocky Mountain elk (Cervus elaphus nelsoni) prion protein gene (PRNP) is pol...
Pathogenesis and transmission of the prion disorders (transmissible spongiform encephalopathies, TSE...
The sequence of the prion protein gene (PRNP) affects susceptibility to spongiform encephalopathies,...
Chronic Wasting Disease (CWD) is a contagious prion disease affecting various species of free-rangin...
The first European cases of chronic wasting disease (CWD) in free-ranging reindeer and wild elk were...
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) that affects member...
The PrP gene encodes the putative causative agent of the transmissible spongiform encepha-lopathies ...
AbstractUntil recently, chronic wasting disease of cervids, the only prion disease affecting wildlif...