Reduced-intensity conditioning regimens have demonstrated lower toxicity but increased relapse rates in the context of allogeneic hematopoietic stem cell transplantation (aSCT) for patients with acute myelogenous leukemia (AML). The FLAMSA- reduced-intensity conditioning (RIC) regimen, combining a cytoreductive and a transplant-conditioning part, has been described to be efficacious in patients with refractory disease. We retrospectively analyzed clinical data of 130 patients with AML after aSCT following FLAMSA RIC at our center. The median follow-up was 37 (10-125) months. The 4-yr overall and disease-free survival rates of the whole cohort were 45% and 40%. Cumulative incidence of relapse was 29%, 35%, and 40% at 1, 2, and 4yr. There wer...
Treatment of relapsed/refractory acute lymphoblastic leukemia (RR-ALL) remains a clinical challenge ...
The fludarabine, amsacrine, and cytarabine (FLAMSA)-reduced-intensity conditioning (RIC) protocol ha...
To assess the role of allogeneic stem cell transplantation (SCT) after reduced-intensity conditionin...
The use of myeloablative conditioning (MAC) in the setting of active relapsed/refractory (R/R) acute...
Purpose The toxicity of allogeneic stem-cell transplantation can be substantially reduced using a re...
Post-transplant relapse is the leading cause of treatment failure in acute myeloid leukemia (AML) pa...
To evaluate the efficacy of reduced intensity conditioning (RIC) prior to allogeneic stem cell trans...
International audiencePost-transplant relapse is the leading cause of treatment failure in acute mye...
PURPOSE Reduced-intensity conditioning (RIC) regimens have extended the curative potential of alloge...
There is a lack of large comparative study on the outcomes of reduced intensity conditioning (RIC) i...
There is a lack of large comparative study on the outcomes of reduced intensity conditioning (RIC) i...
Several prospective randomized trials comparing conditioning intensity before allogeneic hematopoiet...
Patients with acute myeloid leukemia (AML) in relapse or refractory to induction therapy have a dism...
BackgroundReduced intensity conditioning (RIC) before allogeneic hematopoietic stem cell transplanta...
Busulfan/fludarabine (BuFlu) is a widely used conditioning regimen for patients with myeloid maligna...
Treatment of relapsed/refractory acute lymphoblastic leukemia (RR-ALL) remains a clinical challenge ...
The fludarabine, amsacrine, and cytarabine (FLAMSA)-reduced-intensity conditioning (RIC) protocol ha...
To assess the role of allogeneic stem cell transplantation (SCT) after reduced-intensity conditionin...
The use of myeloablative conditioning (MAC) in the setting of active relapsed/refractory (R/R) acute...
Purpose The toxicity of allogeneic stem-cell transplantation can be substantially reduced using a re...
Post-transplant relapse is the leading cause of treatment failure in acute myeloid leukemia (AML) pa...
To evaluate the efficacy of reduced intensity conditioning (RIC) prior to allogeneic stem cell trans...
International audiencePost-transplant relapse is the leading cause of treatment failure in acute mye...
PURPOSE Reduced-intensity conditioning (RIC) regimens have extended the curative potential of alloge...
There is a lack of large comparative study on the outcomes of reduced intensity conditioning (RIC) i...
There is a lack of large comparative study on the outcomes of reduced intensity conditioning (RIC) i...
Several prospective randomized trials comparing conditioning intensity before allogeneic hematopoiet...
Patients with acute myeloid leukemia (AML) in relapse or refractory to induction therapy have a dism...
BackgroundReduced intensity conditioning (RIC) before allogeneic hematopoietic stem cell transplanta...
Busulfan/fludarabine (BuFlu) is a widely used conditioning regimen for patients with myeloid maligna...
Treatment of relapsed/refractory acute lymphoblastic leukemia (RR-ALL) remains a clinical challenge ...
The fludarabine, amsacrine, and cytarabine (FLAMSA)-reduced-intensity conditioning (RIC) protocol ha...
To assess the role of allogeneic stem cell transplantation (SCT) after reduced-intensity conditionin...