Nobody doubts that infections have imposed specialisations on the mammalian genome. However sufficient information is usually missing to attribute a specific genomic modification to pressure from a specific pathogen. Recent studies on mechanisms of mammalian resistance against the ubiquitous protozoan parasite, Toxoplasma gondii, have shown that the small rodents presumed to be largely responsible for transmission of the parasite to its definitive host, the domestic cat, possess distinctive recognition proteins, and interferon inducible effector proteins (IRG proteins) that limit the potential virulence of the parasite. The phylogenetic association of the recognition proteins, TLR11 and TLR12, with T. gondii resistance is weak, but there is...
International audienceMost isolates of Toxoplasma from Europe and North America fall into one of thr...
Recent years have witnessed the discovery of a number of secreted proteins in Toxoplasma gondii that...
The severe virulence of Toxoplasma gondii in classical laboratory inbred mouse strains contradicts t...
Nobody doubts that infections have imposed specialisations on the mammalian genome. However sufficie...
Recent studies have revealed remarkable species specificity of the Toll-like receptors (TLRs) TLR11 ...
Recent studies have revealed remarkable species specificity of the Toll-like receptors (TLRs) TLR11 ...
Toxoplasma gondii is a highly successful parasite with a worldwide prevalence. Small rodents are the...
Some strains of the protozoan parasite Toxoplasma gondii (such as RH) are virulent in laboratory mic...
The Immunity Related GTPases (IRG proteins) constitute a large family of interferon-inducible protei...
Virulence in the ubiquitous intracellular protozoon Toxoplasma gondii for its natural intermediate h...
The immunity related GTPases (IRG proteins) constitute a large family of interferon-inducible protei...
Virulence in the ubiquitous intracellular protozoon Toxoplasma gondii for its natural intermediate h...
Virulence of complex pathogens in mammals is generally determined by multiple components of the path...
UnlabelledThe intracellular parasite Toxoplasma gondii infects a wide variety of vertebrate species ...
Virulence of complex pathogens in mammals is generally determined by multiple components of the path...
International audienceMost isolates of Toxoplasma from Europe and North America fall into one of thr...
Recent years have witnessed the discovery of a number of secreted proteins in Toxoplasma gondii that...
The severe virulence of Toxoplasma gondii in classical laboratory inbred mouse strains contradicts t...
Nobody doubts that infections have imposed specialisations on the mammalian genome. However sufficie...
Recent studies have revealed remarkable species specificity of the Toll-like receptors (TLRs) TLR11 ...
Recent studies have revealed remarkable species specificity of the Toll-like receptors (TLRs) TLR11 ...
Toxoplasma gondii is a highly successful parasite with a worldwide prevalence. Small rodents are the...
Some strains of the protozoan parasite Toxoplasma gondii (such as RH) are virulent in laboratory mic...
The Immunity Related GTPases (IRG proteins) constitute a large family of interferon-inducible protei...
Virulence in the ubiquitous intracellular protozoon Toxoplasma gondii for its natural intermediate h...
The immunity related GTPases (IRG proteins) constitute a large family of interferon-inducible protei...
Virulence in the ubiquitous intracellular protozoon Toxoplasma gondii for its natural intermediate h...
Virulence of complex pathogens in mammals is generally determined by multiple components of the path...
UnlabelledThe intracellular parasite Toxoplasma gondii infects a wide variety of vertebrate species ...
Virulence of complex pathogens in mammals is generally determined by multiple components of the path...
International audienceMost isolates of Toxoplasma from Europe and North America fall into one of thr...
Recent years have witnessed the discovery of a number of secreted proteins in Toxoplasma gondii that...
The severe virulence of Toxoplasma gondii in classical laboratory inbred mouse strains contradicts t...