C-type natriuretic peptide (CNP) is a signaling molecule with important roles in mammalian growth and vascular function. Unexpectedly high plasma CNP concentrations have been reported in late gestation ewes, suggesting a possible role during pregnancy. However, the temporal pattern of CNP in maternal circulation, site/s of production and function during pregnancy have not been identified. Consequently, the aim of this PhD project was to address these unexplored aspects of CNP biology in order to improve our understanding of CNP’s role in pregnancy. To characterise the temporal pattern of maternal circulating CNP during pregnancy, a longitudinal survey was conducted in two representative species of ruminant: sheep and red deer. Plasma conce...
880-01Using microarray analysis, a novel gene, receptor transporter protein-4 (RTP4), was identified...
Global nutrient restriction or excess can influence umbilical hemodynamics in sheep fetuses (Chapter...
Objective To determine changes in plasma C–type natriuretic peptide (CNP), a paracrine product of th...
C-type natriuretic peptide (CNP) is a signaling molecule with important roles in mammalian growth an...
Circulating concentrations of C-type natriuretic peptide (CNP) and a related amino terminal fragment...
C-type natriuretic peptide (CNP), a paracrine growth factor promoting vasodilation and angiogenesis,...
Maternal plasma concentrations of C-type natriuretic peptide (CNP) and a co-secreted bioinactive ami...
The factors regulating the greatly elevated concentrations of maternal plasma C-type natriuretic pep...
C-type natriuretic peptide (CNP) circulates at higher levels in the circulation of ewes pregnant wit...
C-type natriuretic peptide (CNP) is a paracrine growth factor with high abundance in CNS tissues and...
Non-pregnant and twin bearing maternal ewes (n = 4) of mixed age were gradually introduced to a hypo...
This thesis focuses on the renin-angiotensin system and atrial natriuretic factors (ANF) two hormona...
The biological activities of the neurohypophyses of pregnant and embryonic sheep, Ovis aries were st...
C-Type natriuretic peptide (CNP) is a vasoactive hormone and the endothelial component of the natriu...
Thesis (Ph.D.), Animal Sciences, Washington State UniversityPregnancy failure during the early stage...
880-01Using microarray analysis, a novel gene, receptor transporter protein-4 (RTP4), was identified...
Global nutrient restriction or excess can influence umbilical hemodynamics in sheep fetuses (Chapter...
Objective To determine changes in plasma C–type natriuretic peptide (CNP), a paracrine product of th...
C-type natriuretic peptide (CNP) is a signaling molecule with important roles in mammalian growth an...
Circulating concentrations of C-type natriuretic peptide (CNP) and a related amino terminal fragment...
C-type natriuretic peptide (CNP), a paracrine growth factor promoting vasodilation and angiogenesis,...
Maternal plasma concentrations of C-type natriuretic peptide (CNP) and a co-secreted bioinactive ami...
The factors regulating the greatly elevated concentrations of maternal plasma C-type natriuretic pep...
C-type natriuretic peptide (CNP) circulates at higher levels in the circulation of ewes pregnant wit...
C-type natriuretic peptide (CNP) is a paracrine growth factor with high abundance in CNS tissues and...
Non-pregnant and twin bearing maternal ewes (n = 4) of mixed age were gradually introduced to a hypo...
This thesis focuses on the renin-angiotensin system and atrial natriuretic factors (ANF) two hormona...
The biological activities of the neurohypophyses of pregnant and embryonic sheep, Ovis aries were st...
C-Type natriuretic peptide (CNP) is a vasoactive hormone and the endothelial component of the natriu...
Thesis (Ph.D.), Animal Sciences, Washington State UniversityPregnancy failure during the early stage...
880-01Using microarray analysis, a novel gene, receptor transporter protein-4 (RTP4), was identified...
Global nutrient restriction or excess can influence umbilical hemodynamics in sheep fetuses (Chapter...
Objective To determine changes in plasma C–type natriuretic peptide (CNP), a paracrine product of th...