Modern societies depend on the proper and resilient functioning of their critical infrastructures (CIs) to support quality of life to their population. The interdependencies of the CI systems, however, make the CIs increasingly vulnerable to several threats; as a result, natural or human-made disasters can cause significant physical, economic, and social disruptions. Since total beforehand protection cannot be guaranteed, CI protection strategies should focus on resilience enhancement at both the pre- and the post-disaster phase for a better response. This thesis first proposes a resilience assessment framework that provides quantitative means to assess infrastructure resilience for interdependent CI systems. The framework is tested within ...