Add to ORKGThe new 3-ethyl carboxy-4-phenyl-6-fluoro-1-tetralone and 3-ethyl carboxy-4-(p-anisyl)-6-fluoro-1-tetralone were synthesized in good yields by chalcone route. They are key intermediates for the synthesis of analogues of podophyllotoxin a naturally occurring lignan compound. It exhibits antimitotic activity and other biological activity. The structure of new compounds were based on spectral and elemental analysis data
Furo 3',4' : 6,7]-naphtho 2,3-e]-1, 4-dioxin-7-one-6, 6a-tetrahydro-10-one-6-phenyl (9) and furo 3',...
Podophyllotoxin derivatives like etoposide 7a, etophos 7b, and teniposide 7c are used clinically as ...
Podophyllotoxin derivatives like etoposide, etophos , and teniposide are used clinically as potent ...
Podophyllotoxin, one of the well-known naturally occurring lignan, has been used as the lead compoun...
Podophyllotoxin is a natural product isolated from two important medicinal plants podophyllum emodi ...
The new compounds 6,6a-dihydro-2,3-dimethoxy-9-nitro–11bH benzo [C]-fluoren 5,7-dione, 6,6a-dihydro-...
The pyrazole analogues of podophyllotoxin were synthesized by the chalcone route. This route attract...
The pyrazole moiety containing analogs of podophyllotoxin as potential antimitotic agents were synth...
3-Ethylcarboxy-4-trimethoxyphenyl-6,7-dimethyl-methylenedioxy-1- tetralone 5 and 3-ethyl carboxy-4-t...
New tetralone acid analogues of podophyllotoxin 7a-c i.e substituted 4-oxo-7-phenyl-4,5,6,7-tetrahyd...
Analogues (5,6,7) of β - apopicropodophyllin 2 have been synthesized from tetralone acid intermedia...
Cyclopropyl ester (8a-f) were synthesized by the cyclopropanation of chalcones (7a-e) in dry benzene...
Podophyllotoxin belongs to the cyclolignan family of natural products.It exhibits cathartic, cytotox...
Tetralone acids 6, 7 and 8 have been synthesised as intermediates for, the synthesis of podophylloto...
We have synthesized four novel derivatives of podophyllotoxin, the chalcone derivatives n...
Furo 3',4' : 6,7]-naphtho 2,3-e]-1, 4-dioxin-7-one-6, 6a-tetrahydro-10-one-6-phenyl (9) and furo 3',...
Podophyllotoxin derivatives like etoposide 7a, etophos 7b, and teniposide 7c are used clinically as ...
Podophyllotoxin derivatives like etoposide, etophos , and teniposide are used clinically as potent ...
Podophyllotoxin, one of the well-known naturally occurring lignan, has been used as the lead compoun...
Podophyllotoxin is a natural product isolated from two important medicinal plants podophyllum emodi ...
The new compounds 6,6a-dihydro-2,3-dimethoxy-9-nitro–11bH benzo [C]-fluoren 5,7-dione, 6,6a-dihydro-...
The pyrazole analogues of podophyllotoxin were synthesized by the chalcone route. This route attract...
The pyrazole moiety containing analogs of podophyllotoxin as potential antimitotic agents were synth...
3-Ethylcarboxy-4-trimethoxyphenyl-6,7-dimethyl-methylenedioxy-1- tetralone 5 and 3-ethyl carboxy-4-t...
New tetralone acid analogues of podophyllotoxin 7a-c i.e substituted 4-oxo-7-phenyl-4,5,6,7-tetrahyd...
Analogues (5,6,7) of β - apopicropodophyllin 2 have been synthesized from tetralone acid intermedia...
Cyclopropyl ester (8a-f) were synthesized by the cyclopropanation of chalcones (7a-e) in dry benzene...
Podophyllotoxin belongs to the cyclolignan family of natural products.It exhibits cathartic, cytotox...
Tetralone acids 6, 7 and 8 have been synthesised as intermediates for, the synthesis of podophylloto...
We have synthesized four novel derivatives of podophyllotoxin, the chalcone derivatives n...
Furo 3',4' : 6,7]-naphtho 2,3-e]-1, 4-dioxin-7-one-6, 6a-tetrahydro-10-one-6-phenyl (9) and furo 3',...
Podophyllotoxin derivatives like etoposide 7a, etophos 7b, and teniposide 7c are used clinically as ...
Podophyllotoxin derivatives like etoposide, etophos , and teniposide are used clinically as potent ...