In our continuous search for plant secondary metabolites that bind to CB and/or opioid receptors, we selected four extracts that showed interesting affinity versus the above mentioned receptors . In particular: the DCM extract obtained from the aerial parts of Stachys glutinosa (SGE) was able to bind with a good affinity both MOR and DOR with a Ki of 10.3 and 9 μg/mL, respectively while the DCM extract from the leaves of Otanthus maritimus (OME) showed good binding affinity to CB1 (Ki = 2.2 μg/mL) and CB2 (Ki = 1.3 μg/mL) and moderate affinity to MOR and DOR. The third was an alkaloid fraction obtained from the MeOH extract of the roots of Withania somnifera (WSAE) that displayed appreciable affinity versus DOR (Ki = 25.5 μg/mL), CB1 (Ki = ...
Infections with gastrointestinal nematodes (GIN) continue to represent a serious challenge to the he...
This session will detail the experience of members of the NASA Ames Prognostic Center of Excellence ...
This research provides information to guide design decisions for healthcare identity systems based o...
The activity of the epidermal growth factor receptor (EGFR) and its interactions with protein tyrosi...
Titel: Nyckeln till budet - En analys av bakomliggande faktorer och deras inverkan på utfallet vid o...
Les matériaux composites sont largement utilisés dans l'industrie en raison de leur bonne tenue méca...
Guanylyl cyclase C (GC-C) is a member of particulate guanylyl cyclases, discovered primarily as the ...
Individuals with higher cardiorespiratory fitness (CRF), most often assessed by measuring maximal ox...
Purpose. The main end point of the study was to compare the surgical performance of robot-assisted p...
International audienceOn a l'habitude de partager la vie de d'Andilly en deux périodes : l'une au se...
Major depressive disorder affects people’s productivity and ability to function in everyday life. Th...
Disease outbreaks are considered to be the main constraint to aquaculture development. The disadvant...
The goal for this study was to examine the performance of quantitative precipitation forecasting (QP...
A bis(phenolate)pyridine pincer ligand (henceforth abbreviated as ONO) has been employed to support ...
Globalment, aquesta tesi mostra diversos fenòmens que s’associen a la reperfusió després de la isquè...
Infections with gastrointestinal nematodes (GIN) continue to represent a serious challenge to the he...
This session will detail the experience of members of the NASA Ames Prognostic Center of Excellence ...
This research provides information to guide design decisions for healthcare identity systems based o...
The activity of the epidermal growth factor receptor (EGFR) and its interactions with protein tyrosi...
Titel: Nyckeln till budet - En analys av bakomliggande faktorer och deras inverkan på utfallet vid o...
Les matériaux composites sont largement utilisés dans l'industrie en raison de leur bonne tenue méca...
Guanylyl cyclase C (GC-C) is a member of particulate guanylyl cyclases, discovered primarily as the ...
Individuals with higher cardiorespiratory fitness (CRF), most often assessed by measuring maximal ox...
Purpose. The main end point of the study was to compare the surgical performance of robot-assisted p...
International audienceOn a l'habitude de partager la vie de d'Andilly en deux périodes : l'une au se...
Major depressive disorder affects people’s productivity and ability to function in everyday life. Th...
Disease outbreaks are considered to be the main constraint to aquaculture development. The disadvant...
The goal for this study was to examine the performance of quantitative precipitation forecasting (QP...
A bis(phenolate)pyridine pincer ligand (henceforth abbreviated as ONO) has been employed to support ...
Globalment, aquesta tesi mostra diversos fenòmens que s’associen a la reperfusió després de la isquè...
Infections with gastrointestinal nematodes (GIN) continue to represent a serious challenge to the he...
This session will detail the experience of members of the NASA Ames Prognostic Center of Excellence ...
This research provides information to guide design decisions for healthcare identity systems based o...