Background: Glanzmann thrombasthenia (GT) is a rare autosomal recessive abnormality of platelet aggregation with quantitative and/or qualitative abnormality of αIIbβ3 integrin. The αIIbβ3 is a platelet fibrinogen receptor, which is required for platelet aggregation, firm adhesion, and also spreading. The disease is more prevalent in the populations with a higher rate of consanguineous marriages as in some Middle Eastern populations including Iraq, Jordan, and Iran. Different types of mutations in ITGA2B and ITGB3 genes have been previously reported to cause the disease. Result: In this study, 16 patients with the clinical diagnosis of GT were studied. Direct sequencing of the exons and exon-intron boundaries of the above genes revealed ...
Glanzmann’s thrombasthenia (GT) is an autosomal recessive inherited bleeding disorder due to a defec...
Background. Glanzmann thrombasthenia (GT) is an auto-somal recessive disorder of platelet function, ...
International audienceBACKGROUND:Macrothrombocytopenia (MTP) is a rare but enigmatic complication of...
Abstract Background Glanzmann thrombasthenia (GT) is a rare autosomal recessive abnormality of plate...
Background: Glanzmann thrombasthenia (GT) is a rare autosomal recessive abnormality of platelet aggr...
Glanzmann thrombasthenia (GT) is an inherited genetic disorder affecting platelets, which is charact...
Glanzmann thrombasthenia (GT) is an autosomal recessive bleeding disorder characterised by quantitat...
Background: Glanzmann Thrombasthenia (GT) results from mutations in the genes ITGA2B and ITGB3, loca...
Quantitative and/or qualitative defects of the platelet membrane glycoprotein IIb/IIIa complex lead ...
Glanzmann's thrombasthenia (GT) is an autosomal recessive inherited platelet function defect th...
Alan Nurden Institut Hospitalo-Universitaire LIRYC, Pessac, FranceCorrespondence: Alan NurdenInstitu...
Glanzmann's thrombasthenia is a rare congenital bleeding disorder characterized by lack of platelet ...
Glanzmann thrombasthenia (GT) is a rare autosomal recessive disease characterized by prolonged bleed...
We report the largest international study on Glanzmann thrombasthenia (GT), an inherited bleeding di...
International audienceGlanzmann thrombasthenia (GT) is a rare autosomal recessive bleeding disorder ...
Glanzmann’s thrombasthenia (GT) is an autosomal recessive inherited bleeding disorder due to a defec...
Background. Glanzmann thrombasthenia (GT) is an auto-somal recessive disorder of platelet function, ...
International audienceBACKGROUND:Macrothrombocytopenia (MTP) is a rare but enigmatic complication of...
Abstract Background Glanzmann thrombasthenia (GT) is a rare autosomal recessive abnormality of plate...
Background: Glanzmann thrombasthenia (GT) is a rare autosomal recessive abnormality of platelet aggr...
Glanzmann thrombasthenia (GT) is an inherited genetic disorder affecting platelets, which is charact...
Glanzmann thrombasthenia (GT) is an autosomal recessive bleeding disorder characterised by quantitat...
Background: Glanzmann Thrombasthenia (GT) results from mutations in the genes ITGA2B and ITGB3, loca...
Quantitative and/or qualitative defects of the platelet membrane glycoprotein IIb/IIIa complex lead ...
Glanzmann's thrombasthenia (GT) is an autosomal recessive inherited platelet function defect th...
Alan Nurden Institut Hospitalo-Universitaire LIRYC, Pessac, FranceCorrespondence: Alan NurdenInstitu...
Glanzmann's thrombasthenia is a rare congenital bleeding disorder characterized by lack of platelet ...
Glanzmann thrombasthenia (GT) is a rare autosomal recessive disease characterized by prolonged bleed...
We report the largest international study on Glanzmann thrombasthenia (GT), an inherited bleeding di...
International audienceGlanzmann thrombasthenia (GT) is a rare autosomal recessive bleeding disorder ...
Glanzmann’s thrombasthenia (GT) is an autosomal recessive inherited bleeding disorder due to a defec...
Background. Glanzmann thrombasthenia (GT) is an auto-somal recessive disorder of platelet function, ...
International audienceBACKGROUND:Macrothrombocytopenia (MTP) is a rare but enigmatic complication of...