Peran Kendali Glukosa Terhadap Kadar Leptin Serum Penderita Diabetes Melitus Tipe 2 di Malang Raya

Background: Type 2 diabetes mellitus (T2DM) is a progressive chronic disease characterized by hyperglycemia due to insulin resistance. Leptin is a hormone produced by adipocytes which plays a role to control of appetite, weight, energy homeostasis and control of blood glucose levels. Leptin is found to mediate insulin secretion and resistance in peripheral tissues. This study aims to look at the role of glucose control on serum leptin levels in T2DM patients.Method: This research was cross sectional study. The respondents are male and female patients diagnosed with T2DM without complications over the age of 40 years. The subjects divided into the controlled group and uncontrolled group. Each control group of data respectively will depend on the serum leptin level using the Human Leptin Elisa Kit EZHL-80SK. Statistical analysis was done by Independent T-Test and Spearman’s correlation test with a significance level of p