Investigation of antioxidant and antimicrobial activities and phytochemical Compounds of essential oil and different extracts of Cymbopogon olivieri (Boiss.) Bor. from Sistan and Baluchestan province

Background: In this study antimicrobial activities, antioxidant activities and phytochemical compounds in the essential oil and extracts of Cumbopogon olivieri were studied.Material & Methods: For investigation of phytochemical compounds such as total phenolic and total flavonoid contents in three extracts (Methanolic, ethanolic and aqueous) and essential oil by Folin-Ciocaltiu, Aluminum Chloride colorimetric and GC-MS methods and antioxidant activities of extracts by two methods (DPPH and FRAP) and antimicrobial activities of essential oil and extracts of Cumbopogon olivieri against three bacteria such as Staphylococcus aureus, Bacillus cereus, Escherichia coli and two fungi such as Candida albicans and Aspergillus niger by two methods (well diffusion and Minimal Inhibitory Concentration (MIC)) respectively.Results: The results showed that, the methanolic extract had maximum total phenolic and flavonoid contents and antioxidant activity and aqueous extract had minimum value of this compounds and activity. In investigation of essential oil, three compounds such as piperitone (82.95), carene (2.493) and limonene were the major constituents. The results of antimicrobial activity showed that, the essential oil and extracts had good inhibition effect on all of bacteria and fungi and this inhibition depends to concentration.Conclusion: Overall, based on the results obtained, the plant can be a good candidate for the treatment of diseases caused by oxidative stress, and diseases caused by pathogenic microbes. Also due to power up the plant in the elimination of pathogens, could be a viable alternative to antibiotics