Add to ORKGBroadly neutralizing antibodies have been isolated that bind the glycan shield of the HIV-1 envelope spike. One such antibody, PGT135, contacts the intrinsic mannose patch of gp120 at the Asn332, Asn392, and Asn386 glycosylation sites. Here, site-specific glycosylation analysis of recombinant gp120 revealed glycan microheterogeneity sufficient to explain the existence of a minor population of virions resistant to PGT135 neutralization. Target microheterogeneity and antibody glycan specificity are therefore important parameters in HIV-1 vaccine design
Broadly neutralizing HIV antibodies (bNAbs) can recognize carbohydrate-dependent epitopes on gp120. ...
A major advance in the search for an HIV vaccine has been the development of a near-native Envelope ...
A major advance in the search for an HIV vaccine has been the development of a near-native Envelope ...
Broadly neutralizing antibodies have been isolated that bind the glycan shield of the HIV-1 envelope...
Broadly neutralizing antibodies have been isolated that bind the glycan shield of the HIV-1 envelope...
In recent years the glycan shield of the HIV-1 envelope spike (Env) has emerged as a potential targe...
<div><p>Understanding the molecular determinants of sensitivity and resistance to neutralizing antib...
The HIV envelope (Env) protein gp120 is protected from antibody recognition by a dense glycan shield...
The HIV-1 surface glycoprotein, gp120, is made of a rapidly mutating protein core and an extensive c...
The HIV-1 surface glycoprotein, gp120, is made of a rapidly mutating protein core and an extensive c...
The surface envelope glycoprotein (SU) of Human immunodeficiency virus type 1 (HIV-1), gp120SU plays...
The envelope spike of HIV is one of the most highly N-glycosylated structures found in nature. Howev...
AbstractThe human immunodeficiency virus (HIV-1) exterior envelope glycoprotein, gp120, mediates rec...
A major advance in the search for an HIV vaccine has been the development of a near-native Envelope ...
The N-linked oligomannose glycans of HIV gp120 are a target for both microbicide and vaccine design....
Broadly neutralizing HIV antibodies (bNAbs) can recognize carbohydrate-dependent epitopes on gp120. ...
A major advance in the search for an HIV vaccine has been the development of a near-native Envelope ...
A major advance in the search for an HIV vaccine has been the development of a near-native Envelope ...
Broadly neutralizing antibodies have been isolated that bind the glycan shield of the HIV-1 envelope...
Broadly neutralizing antibodies have been isolated that bind the glycan shield of the HIV-1 envelope...
In recent years the glycan shield of the HIV-1 envelope spike (Env) has emerged as a potential targe...
<div><p>Understanding the molecular determinants of sensitivity and resistance to neutralizing antib...
The HIV envelope (Env) protein gp120 is protected from antibody recognition by a dense glycan shield...
The HIV-1 surface glycoprotein, gp120, is made of a rapidly mutating protein core and an extensive c...
The HIV-1 surface glycoprotein, gp120, is made of a rapidly mutating protein core and an extensive c...
The surface envelope glycoprotein (SU) of Human immunodeficiency virus type 1 (HIV-1), gp120SU plays...
The envelope spike of HIV is one of the most highly N-glycosylated structures found in nature. Howev...
AbstractThe human immunodeficiency virus (HIV-1) exterior envelope glycoprotein, gp120, mediates rec...
A major advance in the search for an HIV vaccine has been the development of a near-native Envelope ...
The N-linked oligomannose glycans of HIV gp120 are a target for both microbicide and vaccine design....
Broadly neutralizing HIV antibodies (bNAbs) can recognize carbohydrate-dependent epitopes on gp120. ...
A major advance in the search for an HIV vaccine has been the development of a near-native Envelope ...
A major advance in the search for an HIV vaccine has been the development of a near-native Envelope ...