FEM-Based Compression Fracture Risk Assessment in Osteoporotic Lumbar Vertebra L1

This paper presents a finite element method (FEM)-based fracture risk assessment in patient-specific osteoporotic lumbar vertebra L1. The influence of osteoporosis is defined by variation of parameters such as thickness of the cortical shell, the bone volume–total volume ratio (BV/TV), and the trabecular bone score (TBS). The mechanical behaviour of bone is defined using the Ramberg–Osgood material model. This study involves the static and nonlinear dynamic calculations of von Mises stresses and follows statistical processing of the obtained results in order to develop the patient-specific vertebra reliability. In addition, different scenarios of parameters show that the reliability of the proposed model of human vertebra highly decreases with low levels of BV/TV and is critical due to the thinner cortical bone, suggesting high trauma risk by reason of osteoporosis.This article belongs to the Special Issue Biomaterials for Bone Tissue Engineerin